Smits Jasper A J, Minhajuddin Abu, Jarrett Robin B
Department of Psychology, Southern Methodist University, Dedman College, P.O. Box 750442, Dallas, TX 75275, United States.
J Affect Disord. 2009 Apr;114(1-3):271-8. doi: 10.1016/j.jad.2008.08.008. Epub 2008 Sep 18.
Evidence suggests that comorbid depression influences the outcome of cognitive-behavioral treatment for patients presenting with social phobia. Little is known, however, about the influence of comorbid social phobia on the response to cognitive therapy (CT) for depression among adults presenting with recurrent major depressive disorder (MDD). These analyses seek to clarify this relationship.
Patients (N=156) with recurrent DSM-IV MDD entered CT (20% also met DSM-IV criteria for social phobia). Every week during the course of CT, clinicians assessed depressive symptoms and patients completed self-report instruments measuring severity of depression and anxiety.
At presentation, outpatients with comorbid social phobia reported greater levels of depressive symptoms and clinicians rated their impairment as more severe, compared to their counterparts without social phobia. Patients with or without comorbid social phobia did not differ significantly in (1) attrition rates; (2) response or sustained remission rates; (3) time to response or sustained remission; or (4) rate of improvement in symptoms of depression or anxiety.
The lack of domain-specific measures limits inference with respect to the improvements in social anxiety that occur with CT of depression.
These findings introduce the hypothesis that CT for depression may be flexible enough to treat the depressive symptoms of patients presenting with MDD who also suffer from social phobia.
有证据表明,共病的抑郁症会影响社交恐惧症患者认知行为治疗的效果。然而,对于复发性重度抑郁症(MDD)成人患者中,共病的社交恐惧症对抑郁症认知疗法(CT)反应的影响却知之甚少。这些分析旨在阐明这种关系。
156例复发性DSM-IV重度抑郁症患者接受了认知疗法(其中20%也符合DSM-IV社交恐惧症标准)。在认知疗法过程中,临床医生每周评估抑郁症状,患者完成自我报告工具,测量抑郁和焦虑的严重程度。
就诊时,与无社交恐惧症的患者相比,共病社交恐惧症的门诊患者报告的抑郁症状水平更高,临床医生对其损害程度的评定也更严重。有无共病社交恐惧症的患者在以下方面无显著差异:(1)脱落率;(2)缓解或持续缓解率;(3)达到缓解或持续缓解的时间;(4)抑郁或焦虑症状的改善率。
缺乏特定领域的测量方法限制了对抑郁症认知疗法后社交焦虑改善情况的推断。
这些发现提出了一个假设,即抑郁症的认知疗法可能足够灵活,能够治疗同时患有社交恐惧症的MDD患者的抑郁症状。