Elsayed Elsayed A, El Enshasy Hesham, Wadaan Mohammad A M, Aziz Ramlan
Bioproducts Research Chair, Zoology Department, Faculty of Science, King Saud University, Riyadh 11451, Saudi Arabia ; Natural and Microbial Products Department, National Research Centre, Dokki, Cairo 12311, Egypt.
Institute of Bioproduct Development (IBD), Universiti Teknologi Malaysia (UTM), 81130 Skudai, Malaysia ; City of Scientific Research and Technology Application, New Burg Al Arab, Alexandria 21934, Egypt.
Mediators Inflamm. 2014;2014:805841. doi: 10.1155/2014/805841. Epub 2014 Nov 23.
For centuries, macrofungi have been used as food and medicine in different parts of the world. This is mainly attributed to their nutritional value as a potential source of carbohydrates, proteins, amino acids, and minerals. In addition, they also include many bioactive metabolites which make mushrooms and truffles common components in folk medicine, especially in Africa, the Middle East, China, and Japan. The reported medicinal effects of mushrooms include anti-inflammatory effects, with anti-inflammatory compounds of mushrooms comprising a highly diversified group in terms of their chemical structure. They include polysaccharides, terpenoids, phenolic compounds, and many other low molecular weight molecules. The aims of this review are to report the different types of bioactive metabolites and their relevant producers, as well as the different mechanisms of action of mushroom compounds as potent anti-inflammatory agents.
几个世纪以来，大型真菌在世界不同地区一直被用作食物和药物。这主要归因于它们作为碳水化合物、蛋白质、氨基酸和矿物质潜在来源的营养价值。此外，它们还含有许多生物活性代谢产物，这使得蘑菇和块菌成为民间医学中的常见成分，尤其是在非洲、中东、中国和日本。据报道，蘑菇的药用功效包括抗炎作用，蘑菇中的抗炎化合物在化学结构上构成了一个高度多样化的群体。它们包括多糖、萜类化合物、酚类化合物以及许多其他低分子量分子。本综述的目的是报告不同类型的生物活性代谢产物及其相关生产者，以及蘑菇化合物作为强效抗炎剂的不同作用机制。
Zotero 插件
