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一名患有获得性免疫缺陷综合征的婴儿的巨细胞病毒性视网膜炎。

Cytomegalovirus retinitis in an infant with acquired immunodeficiency syndrome.

作者信息

Levin A V, Zeichner S, Duker J S, Starr S E, Augsburger J J, Kronwith S

机构信息

Retina Department, Wills Eye Hospital, Philadelphia, Pennsylvania.

出版信息

Pediatrics. 1989 Oct;84(4):683-7.

PMID:2550878
Abstract

A case of cytomegalovirus retinitis in an infant with acquired immunodeficiency syndrome (AIDS) is described. Although well recognized as an ocular manifestation of AIDS in adults, only one case of the necrotic retinitis caused by cytomegalovirus has been described in a child with AIDS. Intravenous treatment with ganciclovir resulted in substantial ocular improvement, despite the advanced nature of the disease in one eye in which there was also secondary neovascular glaucoma. Home maintenance treatment was used via Broviac catheter. The patient later died following pulmonary infection with Pneumocystis carinii.

摘要

本文描述了一例患有获得性免疫缺陷综合征(AIDS)的婴儿发生巨细胞病毒性视网膜炎的病例。虽然巨细胞病毒性视网膜炎作为成人艾滋病的眼部表现已广为人知,但在患有艾滋病的儿童中,仅报道过一例由巨细胞病毒引起的坏死性视网膜炎。尽管该疾病在一只眼睛已发展至晚期并伴有继发性新生血管性青光眼,但静脉注射更昔洛韦治疗后,眼部情况有了显著改善。通过 Broviac 导管进行家庭维持治疗。该患者后来因卡氏肺孢子虫肺部感染而死亡。

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1
Cytomegalovirus retinitis in an infant with acquired immunodeficiency syndrome.一名患有获得性免疫缺陷综合征的婴儿的巨细胞病毒性视网膜炎。
Pediatrics. 1989 Oct;84(4):683-7.
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[Foudroyant course of AIDS-induced cytomegalovirus retinitis].
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Retinal and gastrointestinal disease due to cytomegalovirus in patients with the acquired immune deficiency syndrome: prevalence, natural history, and response to ganciclovir therapy.获得性免疫缺陷综合征患者中由巨细胞病毒引起的视网膜和胃肠道疾病:患病率、自然史及对更昔洛韦治疗的反应
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Retinal manifestations of the acquired immune deficiency syndrome (AIDS): cytomegalovirus, candida albicans, cryptococcus, toxoplasmosis and Pneumocystis carinii.获得性免疫缺陷综合征(艾滋病)的视网膜表现:巨细胞病毒、白色念珠菌、隐球菌、弓形虫病和卡氏肺孢子虫。
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引用本文的文献

1
Long term therapy of cytomegalovirus retinitis with ganciclovir in a child with acquired immunodeficiency syndrome.用更昔洛韦对一名获得性免疫缺陷综合征儿童进行巨细胞病毒性视网膜炎的长期治疗。
Can J Infect Dis. 1993 Jan;4(1):15-20. doi: 10.1155/1993/576891.
2
Report of a case of aggressive cytomegalovirus retinitis in an infant with AIDS.一例患艾滋病婴儿发生侵袭性巨细胞病毒性视网膜炎的病例报告。
Int Ophthalmol. 1996;20(6):333-7. doi: 10.1007/BF00176887.
3
The spectrum of eye disease in children with AIDS due to vertically transmitted HIV disease: clinical findings, virology and recommendations for surveillance.
Graefes Arch Clin Exp Ophthalmol. 1997 Mar;235(3):125-9. doi: 10.1007/BF00941718.
4
Pediatric human immunodeficiency virus infection.小儿人类免疫缺陷病毒感染
Clin Microbiol Rev. 1996 Oct;9(4):448-68. doi: 10.1128/CMR.9.4.448.
5
Foscarnet. A review of its antiviral activity, pharmacokinetic properties and therapeutic use in immunocompromised patients with cytomegalovirus retinitis.膦甲酸钠。对其在免疫功能低下的巨细胞病毒性视网膜炎患者中的抗病毒活性、药代动力学特性及治疗应用的综述。
Drugs. 1991 Jan;41(1):104-29. doi: 10.2165/00003495-199141010-00009.