Matsui O, Kadoya M, Kameyama T, Yoshikawa J, Arai K, Gabata T, Takashima T, Nakanuma Y, Terada T, Ida M
Department of Radiology, Kanazawa University School of Medicine, Japan.
Radiology. 1989 Oct;173(1):123-6. doi: 10.1148/radiology.173.1.2550995.
Differentiation of hepatocellular carcinomas from adenomatous hyperplastic nodules (AHNs) is important for the early and precise detection of hepatocellular carcinoma in the cirrhotic liver. For this purpose, the authors compared findings on magnetic resonance (MR) images of surgically resected AHNs (n = 7) with those of hepatocellular carcinoma (n = 47). AHNs were divided into two histologic groups: those without atypia (n = 5) and those with atypical hepatocytes or malignant foci (n = 2). All AHNs without atypia were hyperintense on T1-weighted spin-echo images and hypointense on T2-weighted spin-echo images relative to the surrounding liver. However, almost all hepatocellular carcinomas, except for two lesions with massive coagulation necrosis, were demonstrated as hyperintense on T2-weighted images. MR imaging may be useful in the differentiation of AHN without atypia from hepatocellular carcinoma in the cirrhotic liver.
在肝硬化肝脏中，鉴别肝细胞癌与腺瘤样增生结节（AHN）对于早期准确检测肝细胞癌至关重要。为此，作者比较了手术切除的AHN（n = 7）与肝细胞癌（n = 47）的磁共振（MR）图像表现。AHN分为两个组织学组：无异型性的（n = 5）和有异型肝细胞或恶性病灶的（n = 2）。相对于周围肝脏，所有无异型性的AHN在T1加权自旋回波图像上呈高信号，在T2加权自旋回波图像上呈低信号。然而，除了两个有大片凝固性坏死的病灶外，几乎所有肝细胞癌在T2加权图像上均表现为高信号。MR成像可能有助于在肝硬化肝脏中鉴别无异型性的AHN与肝细胞癌。
