Sinha Gautam, Gupta Shikha, Temkar Shreyas, Pandey Veena, Sihota Ramanjit, Dada Tanuj
Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, 110029, India.
Int Ophthalmol. 2015 Feb;35(1):89-93. doi: 10.1007/s10792-014-0026-6. Epub 2014 Dec 16.
To analyze correlation of intraocular pressure (IOP) measurement between new rebound tonometer (RBT) I-Care TA01 and Goldmann applanation tonometer (GAT). One hundred eighty-five eyes of 185 subjects presenting with glaucoma or cataract were enrolled in the study. In all patients, IOP was obtained by an ophthalmologist using I-Care TA01 and GAT. IOP between the two were compared at range of 8-15, 16-21, and >22 mmHg and difference was considered as significant at p < 0.05 (t test). Bland-Altman analysis tested agreement between instruments overall and for each subgroup of patients with glaucoma or no glaucoma (cataract only). Of 185 patients, 86 had glaucoma; 99 did not. Mean age of patients was 55.77 ± 14.46 years; with no difference between the two subgroups (p = 0.12). There was no significant difference in mean IOP between the two tonometers at IOP between 8-15 mmHg (p = 0.097) and 16-21 mmHg (p = 0.51). However, a significant difference was observed between the two at IOP > 22 mmHg (p = 0.023) with mean GAT (24.8 mmHg) being higher than mean RBT (23.16 mmHg). Overall, there was no difference between the two (p = 0.59) and they had a high correlation (Pearson correlation r = 0.815; p = 0.01). The mean difference between the two was 0.1 (95 % agreement limits: UL +6 (1.96SD), LL -5.8 (-1.96SD)), in patients with no glaucoma was 0.091 (95 % AL: UL +4.8 (1.96SD), LL -4.6 (-1.96SD)), and in patients with glaucoma was 0.151 (95 % AL: UL +7.25 (1.96SD), LL -6.9 (-1.96SD)). RBT I-Care TA01 and Goldmann tonometer cannot be used interchangeably due to large limits of agreement.
分析新型回弹式眼压计（RBT）I-Care TA01与戈德曼压平眼压计（GAT）测量眼压（IOP）之间的相关性。本研究纳入了185例患有青光眼或白内障的受试者的185只眼睛。所有患者均由眼科医生使用I-Care TA01和GAT测量眼压。比较了两者在8 - 15mmHg、16 - 21mmHg和>22mmHg范围内的眼压，差异在p < 0.05时被认为具有显著性（t检验）。Bland-Altman分析测试了两种仪器总体之间以及青光眼患者或非青光眼患者（仅白内障患者）各亚组之间的一致性。185例患者中，86例患有青光眼；99例未患青光眼。患者的平均年龄为55.77±14.46岁；两组之间无差异（p = 0.12）。在8 - 15mmHg（p = 0.097）和16 - 21mmHg（p = 0.51）的眼压下，两种眼压计的平均眼压无显著差异。然而，在眼压>22mmHg时，两者之间观察到显著差异（p = 0.023），GAT的平均眼压（24.8mmHg）高于RBT的平均眼压（23.16mmHg）。总体而言，两者之间无差异（p = 0.59），且具有高度相关性（Pearson相关系数r = 0.815；p = 0.01）。两者之间的平均差异为0.1（95%一致性界限：上限+6（1.96标准差），下限-5.8（-1.96标准差）），在非青光眼患者中为0.091（95%一致性界限：上限+4.8（1.96标准差），下限-4.6（-1.96标准差）），在青光眼患者中为0.151（95%一致性界限：上限+7.25（1.96标准差），下限-6.9（-1.96标准差））。由于一致性界限较大，RBT I-Care TA01和戈德曼眼压计不能互换使用。
