人工耳蜗植入儿童的眼震和颈前庭诱发肌源性电位
Ocular and cervical vestibular-evoked myogenic potentials in children with cochlear implant.
作者信息
Xu Xin-Da, Zhang Xiao-Tong, Zhang Qing, Hu Juan, Chen Yan-Fei, Xu Min
机构信息
Department of Otorhinolaryngology Head and Neck Surgery, Second Affiliated Hospital, Xi'an Jiaotong University College of Medicine, Ear Institute of Xi'an Jiaotong University College of Medicine, Xi'an, China; Department of Otology and Skull Base Surgery, Eye Ear Nose & Throat Hospital, Fudan University, Shanghai 200031, China; Key Laboratory of Hearing Science, Ministry of Health, Shanghai, China.
Department of Otorhinolaryngology Head and Neck Surgery, Second Affiliated Hospital, Xi'an Jiaotong University College of Medicine, Ear Institute of Xi'an Jiaotong University College of Medicine, Xi'an, China.
出版信息
Clin Neurophysiol. 2015 Aug;126(8):1624-31. doi: 10.1016/j.clinph.2014.10.216. Epub 2014 Nov 13.
OBJECTIVE
To define the profile of ocular and cervical vestibular-evoked myogenic potentials (oVEMPs and cVEMPs) in children with cochlear implant (CI), we studied air-conducted sound (ACS)-evoked responses pre- and postoperatively.
METHODS
The ACS-evoked oVEMPs and cVEMPs of 31 children with cochlear implantation were investigated. Thresholds, amplitudes, P1 and N1 latencies, and interpeak latencies of VEMPs were measured and analyzed.
RESULTS
Before CI, the response rates of oVEMPs and cVEMPs were 71.0% and 67.7%, respectively. The oVEMPs and cVEMPs on the operated side disappeared after CI, which resulted in a decrease in response rates, whether the device was switched on (12.9% and 32. 0%) or off (19.2% and 34.8%). In the case when VEMPs could be elicited on the operated side after CI, the parameters of waveforms showed abnormal changes, including threshold elevation (maximum of 8.34-dB SPL in oVEMP and 8.75-dB SPL in cVEMP) and amplitude decrease (maximum of 4.10μV in oVEMP and 191.82μV in cVEMP).
CONCLUSIONS
Disappearance and impairment of VEMPs could be observed after CI, and the waveforms of oVEMP and cVEMP could reflect the degree of damage to the utricle and saccule caused by CI and other related factors.
SIGNIFICANCE
The oVEMPs and cVEMPs prove to be accurate methods to evaluate vestibular function in children with CI.
目的
为了明确人工耳蜗植入（CI）儿童的眼震和颈前庭诱发肌源性电位（oVEMP和cVEMP）特征，我们研究了术前和术后气导声音（ACS）诱发的反应。
方法
对31例人工耳蜗植入儿童的ACS诱发oVEMP和cVEMP进行了研究。测量并分析了VEMP的阈值、振幅、P1和N1潜伏期以及峰间潜伏期。
结果
人工耳蜗植入前，oVEMP和cVEMP的反应率分别为71.0%和67.7%。人工耳蜗植入后，患侧的oVEMP和cVEMP消失，导致反应率下降，无论设备是否开启（分别为12.9%和32.0%）或关闭（分别为19.2%和34.8%）。在人工耳蜗植入后患侧仍可引出VEMP的情况下，波形参数出现异常变化，包括阈值升高（oVEMP最大升高8.34 dB SPL，cVEMP最大升高8.75 dB SPL）和振幅降低（oVEMP最大降低4.10μV，cVEMP最大降低191.82μV）。
结论
人工耳蜗植入后可观察到VEMP消失和受损，oVEMP和cVEMP波形可反映人工耳蜗植入及其他相关因素对椭圆囊和球囊的损伤程度。
意义
oVEMP和cVEMP被证明是评估人工耳蜗植入儿童前庭功能的准确方法。
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