Tambasco Nicola, Simoni Simone, Eusebi Paolo, Ripandelli Francesco, Brahimi Elona, Sacchini Elisa, Nigro Pasquale, Marsili Erica, Calabresi Paolo
Clinica Neurologica, Azienda Ospedaliero-Universitaria di Perugia, Perugia, Italy,
Neurol Sci. 2015 May;36(5):759-64. doi: 10.1007/s10072-014-2037-5. Epub 2014 Dec 17.
Freezing of gait (FOG) is a common and disabling symptom in Parkinson's disease (PD) and its staging is complex because of its episodic nature. Patient-reported assessments are essential in evaluating this disabling symptom. The Freezing of Gait Questionnaire (FOG-Q) is considered a valid and reliable tool for the assessment of FOG severity. The aim of our study was to validate the Italian version of FOG-Q and to investigate for its association with several clinical aspects of PD. Fifty-one PD patients were administered the FOG-Q and the timed up and go test. Moreover, patients were evaluated for the unified PD rating scale (UPDRS), the Hoehn and Yahr Scale (H&Y) and the falls-efficacy scale [FES(S)]. Mean (SD) FOG-Q item scores ranged between 1.5 and 2.7 (1.0-1.4); corrected item-total correlations ranged between 0.63 and 0.86. The total FOG-Q score ranged between 0 and 24, with a mean + SD of 12.6 (6.2) and a median (q1-q3) of 12 (9-17). Reliability was 0.91. FOG-Q correlated with H&Y (0.36, p = 0.0091), UPDRS part III (rS = 0.27, p = 0.054), PD duration (rS = 0.35, p < 0.01), FES(S) (rS = 0.58, p < 0.001) and the timed up and go test (rS = 0.51, p = 0.001). Non-significant positive correlations were observed for dyskinesia and motor fluctuations. Our study validates the Italian version of the FOG-Q, in that it results being a reliable instrument for assessing FOG in PD patients.
冻结步态（FOG）是帕金森病（PD）中一种常见且致残的症状，由于其发作性特点，其分期较为复杂。患者报告的评估对于评估这种致残症状至关重要。冻结步态问卷（FOG-Q）被认为是评估FOG严重程度的有效且可靠的工具。我们研究的目的是验证FOG-Q的意大利语版本，并调查其与PD的几个临床方面的关联。对51名PD患者进行了FOG-Q和计时起立行走测试。此外，对患者进行了统一帕金森病评定量表（UPDRS）、 Hoehn和Yahr量表（H&Y）以及跌倒效能量表[FES(S)]的评估。平均（标准差）FOG-Q项目得分在1.5至2.7之间（1.0 - 1.4）；校正后的项目总分相关性在0.63至0.86之间。FOG-Q总分在0至24之间，平均 + 标准差为12.6（6.2），中位数（q1 - q3）为12（9 - 17）。信度为0.91。FOG-Q与H&Y相关（0.36，p = 0.0091）、UPDRS第三部分（rS = 0.27，p = 0.054）、PD病程（rS = 0.35，p < 0.01）、FES(S)（rS = 0.58，p < 0.001）以及计时起立行走测试（rS = 0.51，p = 0.001）。对于异动症和运动波动，观察到无显著的正相关性。我们的研究验证了FOG-Q的意大利语版本，因为它是评估PD患者FOG的可靠工具。
