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患有女性盆底功能障碍的老年女性的衰弱、认知障碍和功能残疾

Frailty, cognitive impairment, and functional disability in older women with female pelvic floor dysfunction.

作者信息

Erekson Elisabeth A, Fried Terri R, Martin Deanna K, Rutherford Thomas J, Strohbehn Kris, Bynum Julie P W

机构信息

Department of Obstetrics and Gynecology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA,

出版信息

Int Urogynecol J. 2015 Jun;26(6):823-30. doi: 10.1007/s00192-014-2596-2. Epub 2014 Dec 17.

Abstract

INTRODUCTION AND HYPOTHESIS

There is a growing body of evidence demonstrating frailty as an important predictor of surgical outcomes in older adults undergoing major surgeries. The age-related onset of many symptoms of female pelvic floor dysfunction (PFD) in women suggests that many women seeking treatment for PFD may also have a high prevalence of frailty, which could potentially impact the risks and benefits of surgical treatment options. Our primary objective was to determine the prevalence of frailty, cognitive impairment, and functional disability in older women seeking treatment for PFD.

METHODS

We conducted a cross-sectional study with prospective recruitment between September 2011 and September 2012. Women, age 65 years and older, were recruited at the conclusion of their new patient consultation for PFD at a tertiary center. A comprehensive geriatric screening including frailty measurements (Fried Frailty Index), cognitive screening (Saint Louis University Mental Status score), and functional status evaluation for activities of daily living (Katz ADL score) was conducted.

RESULTS

Sixteen percent (n/N = 25/150) of women were categorized as frail according to the Fried Frailty Index score. After adjusting for education level, 21.3 % of women (n/N = 32/150) screened positive for dementia and 46 (30.7 %) reported functional difficulty or dependence in performing at least one Katz ADL. Sixty-nine women (46.0 %) chose surgical options for treatment of their PFD at the conclusion of their new patient visit with their physician.

CONCLUSIONS

Frailty, cognitive impairment, and functional disability are common in older women seeking treatment for PFD.

摘要

引言与假设

越来越多的证据表明,衰弱是接受大手术的老年人手术结局的重要预测指标。女性盆底功能障碍(PFD)的许多症状与年龄相关,这表明许多寻求PFD治疗的女性也可能有较高的衰弱患病率,这可能会影响手术治疗方案的风险和益处。我们的主要目标是确定寻求PFD治疗的老年女性中衰弱、认知障碍和功能残疾的患病率。

方法

我们在2011年9月至2012年9月期间进行了一项前瞻性招募的横断面研究。65岁及以上的女性在三级中心完成新患者PFD咨询时被招募。进行了全面的老年筛查,包括衰弱测量(弗里德衰弱指数)、认知筛查(圣路易斯大学精神状态评分)和日常生活活动功能状态评估(卡茨ADL评分)。

结果

根据弗里德衰弱指数评分,16%(n/N = 25/150)的女性被归类为衰弱。在调整教育水平后,21.3%的女性(n/N = 32/150)痴呆筛查呈阳性,46名(30.7%)女性报告在至少一项卡茨ADL中存在功能困难或依赖。69名女性(46.0%)在与医生的新患者就诊结束时选择了手术治疗PFD。

结论

衰弱、认知障碍和功能残疾在寻求PFD治疗的老年女性中很常见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0dcf/4713028/6dc9ad39e182/nihms705821f1.jpg

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