From the Division of Urogynecology, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh Medical Center, Pittsburgh, PA.
Department of Obstetrics and Gynecology, George Washington School of Medicine and Health Sciences, Washington, DC.
Urogynecology (Phila). 2023 Feb 1;29(2):168-174. doi: 10.1097/SPV.0000000000001289.
Acute postoperative urinary retention (POUR) is common after pelvic reconstructive surgery, occurring in 15-45% of women. There is a paucity of data on the relationship between frailty and POUR after prolapse surgery.
This study aimed to examine the association between frailty and POUR in older women who underwent pelvic organ prolapse surgery.
This secondary analysis of a prospective study of postoperative delirium enrolled women 60 years and older undergoing prolapse surgery. The Fried Frailty Index was used to assess frailty before surgery. Acute POUR was defined as failure to pass a retrograde voiding trial at hospital discharge with postvoid residual volume of greater than 100 mL.
Analyses included 165 women, with a mean ± SD age of 72.5 ± 6.1 years and a body mass index of 28.0 ± 4.4 kg/m2. There were 49 laparoscopic/robotic apical suspension procedures (29.7%), 60 vaginal obliterative procedures (36.4%), 47 vaginal apical suspension procedures (28.5%), and 9 isolated anterior and/or posterior colporrhaphies (5.5%), of which 9 had a concomitant incontinence procedure. Seventy-eight women (47.3%) experienced acute POUR. Thirty-one (18.8%) met the criteria for "not frail," 115 (88.5%) were "prefrail," and 19 (11.5%) were "frail." Neither frailty status nor score was associated with POUR. In an analysis of individual Fried Frailty Index components, self-reported unintentional weight loss was significantly associated with POUR (odds ratio, 4.6; 95% confidence interval, 1.23-17.15). This remained significant on multivariable logistic regression (adjusted odds ratio, 4.06; 95% confidence interval, 1.01-16.39).
Frailty was not associated with POUR in older women undergoing prolapse surgery. The observed association between POUR and unintended weight loss before surgery warrants further investigation.
急性术后尿潴留(POUR)是骨盆重建手术后的常见并发症,发生在 15-45%的女性中。关于虚弱与脱垂手术后 POUR 之间的关系,数据很少。
本研究旨在探讨老年女性盆腔器官脱垂手术后虚弱与 POUR 之间的关系。
这是一项对术后谵妄前瞻性研究的二次分析,纳入了 60 岁及以上行脱垂手术的女性。术前采用 Fried 虚弱指数评估虚弱程度。急性 POUR 定义为出院时逆行排尿试验失败,且残余尿量大于 100ml。
分析纳入了 165 名女性,平均年龄(SD)为 72.5(6.1)岁,体重指数(BMI)为 28.0(4.4)kg/m2。其中 49 例采用腹腔镜/机器人顶悬术(29.7%),60 例行阴道闭合术(36.4%),47 例行阴道顶悬术(28.5%),9 例行孤立的前、/或后阴道修补术(5.5%),其中 9 例同时行尿失禁手术。78 例(47.3%)发生急性 POUR。31 例(18.8%)符合“非虚弱”标准,115 例(88.5%)为“虚弱前期”,19 例(11.5%)为“虚弱”。虚弱状态或评分均与 POUR 无关。在对 Fried 虚弱指数各成分的分析中,自我报告的非故意体重减轻与 POUR 显著相关(比值比,4.6;95%置信区间,1.23-17.15)。多变量逻辑回归分析(调整比值比,4.06;95%置信区间,1.01-16.39)结果仍显著。
在接受脱垂手术的老年女性中,虚弱与 POUR 无关。术前 POUR 与非故意体重减轻之间的观察到的关联值得进一步研究。