Nguyen M H, Bryant K, O'Neill S G
1 Rheumatology Department, Liverpool Hospital, Australia.
2 SWS Clinical School, University of New South Wales, and the Ingham Institute for Applied Medical Research, Australia.
Lupus. 2018 Nov;27(13):2003-2011. doi: 10.1177/0961203318796293. Epub 2018 Aug 29.
Fatigue is a common, disabling problem that is highly prevalent in patients with systemic lupus erythematous (SLE). More recently, vitamin D status has been established as a potential contributor to SLE pathogenesis and manifestations, in particular fatigue. This review summarizes the literature regarding the role of vitamin D in SLE, and provides an overview of the recent literature examining the association between vitamin D and fatigue in patients with SLE. Finally, the role of vitamin D supplementation in the treatment of SLE-related fatigue is considered.
疲劳是一种常见的、使人衰弱的问题，在系统性红斑狼疮（SLE）患者中非常普遍。最近，维生素D状态已被确定为SLE发病机制和表现的潜在促成因素，尤其是疲劳。本综述总结了关于维生素D在SLE中作用的文献，并概述了最近研究SLE患者维生素D与疲劳之间关联的文献。最后，考虑了补充维生素D在治疗SLE相关疲劳中的作用。
