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英国的地球化学环境与心血管疾病:食物和水中的镁

The UK geochemical environment and cardiovascular diseases: magnesium in food and water.

作者信息

Davies B E

机构信息

Clemson University, Clemson, SC, USA,

出版信息

Environ Geochem Health. 2015 Jun;37(3):411-27. doi: 10.1007/s10653-014-9671-y. Epub 2014 Dec 21.

Abstract

Cardiovascular diseases (CVDs) contribute approximately one-third to noncommunicable diseases in the UK. The central role of magnesium in CVDs (enzyme activity, cardiac signalling, etc.) is well established. Mortality and morbidity rates for CVDs may be inversely related to water hardness, suggesting a role for environmental magnesium. Published official and quasi-official data sources were evaluated to establish a model magnesium intake for a representative adult: standardised reference individual (SRI), standardised reference male (SRM) or standardised reference female (SRF). For typical dietary constituents, only tap water is probably locally derived and bottled water may not be. Fruits and vegetables are imported from many countries, while meat, dairy and cereal products represent a composite of UK source areas. Alcoholic beverages provide magnesium, there is doubt about its absorptive efficiency, and they are not locally derived. A simple model was devised to examine the effect of varying dietary contributions to total daily intake of magnesium. Omitting tap or bottled water, the combined intake, solid food plus alcoholic beverages, is 10.57 mmol Mg (84.5 % RNI) for the SRM and for the SRF, 8.10 mmol Mg (71.7 % RNI). Consumers drinking water derived from reservoirs or rivers, or supplementing it with the purest bottled water, improve their magnesium intake only slightly compared with water containing no magnesium. Choosing bottled water with high magnesium content when the public supply derives from rivers or reservoirs partially satisfies magnesium needs. Real improvement in SRI magnesium nutrition is seen only where water is hard. However, this conclusion cannot be validated until new measurement technologies for body magnesium become available.

摘要

在英国,心血管疾病(CVDs)约占非传染性疾病的三分之一。镁在心血管疾病中的核心作用(酶活性、心脏信号传导等)已得到充分证实。心血管疾病的死亡率和发病率可能与水的硬度呈负相关,这表明环境中的镁可能发挥了作用。我们评估了已发布的官方和准官方数据来源,以确定具有代表性的成年人(标准化参考个体[SRI]、标准化参考男性[SRM]或标准化参考女性[SRF])的镁摄入量模型。对于典型的饮食成分,可能只有自来水是本地获取的,而瓶装水可能并非如此。水果和蔬菜从许多国家进口,而肉类、奶制品和谷物产品则代表了英国多个产地的综合情况。酒精饮料能提供镁,但对其吸收效率存在疑问,且并非本地生产。我们设计了一个简单模型来研究不同饮食成分对每日镁总摄入量的影响。对于SRM,若不考虑自来水或瓶装水,固体食物加酒精饮料的镁联合摄入量为10.57 mmol(占推荐营养素摄入量的84.5%);对于SRF,为8.10 mmol(占推荐营养素摄入量的71.7%)。与饮用不含镁的水相比,饮用来自水库或河流的水或补充最纯净的瓶装水的消费者,其镁摄入量仅略有提高。当公共供水来自河流或水库时,选择高镁含量的瓶装水只能部分满足镁的需求。只有在水硬度较高的地区,SRI的镁营养状况才会有真正改善。然而,在有新的人体镁测量技术可用之前,这一结论无法得到验证。

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