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用于在临床样本中鉴定甲型H7N9禽流感病毒的快速诊断检测

Rapid diagnostic tests for identifying avian influenza A(H7N9) virus in clinical samples.

作者信息

Chen Yu, Wang Dayan, Zheng Shufa, Shu Yuelong, Chen Wenxiang, Cui Dawei, Li Jinming, Yu Hongjie, Wang Yu, Li Lanjuan, Shang Hong

出版信息

Emerg Infect Dis. 2015 Jan;21(1):87-90. doi: 10.3201/eid2101.140247.

DOI:10.3201/eid2101.140247
PMID:25529064
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4285248/
Abstract

To determine sensitivity of rapid diagnostic tests for detecting influenza A(H7N9) virus, we compared rapid tests with PCR results and tested different types of clinical samples. Usefulness of seasonal influenza rapid tests for A(H7N9) virus infections is limited because of their low sensitivity for detecting virus in upper respiratory tract specimens.

摘要

为确定快速诊断检测对甲型H7N9流感病毒的检测敏感性,我们将快速检测结果与聚合酶链反应(PCR)结果进行比较,并对不同类型的临床样本进行检测。由于季节性流感快速检测对上呼吸道标本中病毒的检测敏感性较低,其在甲型H7N9流感病毒感染检测中的作用有限。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15be/4285248/d9c86c7b2abb/14-0247-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15be/4285248/1f6b72b23da0/14-0247-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15be/4285248/d9c86c7b2abb/14-0247-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15be/4285248/1f6b72b23da0/14-0247-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15be/4285248/d9c86c7b2abb/14-0247-F2.jpg

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2
Development of a smartphone-based rapid dual fluorescent diagnostic system for the simultaneous detection of influenza A and H5 subtype in avian influenza A-infected patients.基于智能手机的快速双重荧光诊断系统的开发,用于同时检测甲型流感病毒 A 和 H5 亚型在感染禽流感患者中的应用。
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3

本文引用的文献

1
Biological features of novel avian influenza A (H7N9) virus.新型甲型 H7N9 禽流感病毒的生物学特征。
Nature. 2013 Jul 25;499(7459):500-3. doi: 10.1038/nature12379. Epub 2013 Jul 3.
2
A comparison of rapid point-of-care tests for the detection of avian influenza A(H7N9) virus, 2013.2013年用于检测甲型H7N9禽流感病毒的即时检测快速检测方法比较
Euro Surveill. 2013 May 23;18(21):20487.
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Clinical findings in 111 cases of influenza A (H7N9) virus infection.111 例甲型 H7N9 流感病毒感染的临床特征。
Improvement of a rapid diagnostic application of monoclonal antibodies against avian influenza H7 subtype virus using Europium nanoparticles.
利用铕纳米粒子改进针对禽流感 H7 亚型病毒的单克隆抗体快速诊断应用。
Sci Rep. 2017 Aug 11;7(1):7933. doi: 10.1038/s41598-017-08328-9.
4
Evaluation of Commercial Diagnostic Assays for the Specific Detection of Avian Influenza A (H7N9) Virus RNA Using a Quality-Control Panel and Clinical Specimens in China.在中国使用质量控制样本和临床标本对用于特异性检测甲型禽流感(H7N9)病毒RNA的商业诊断检测方法进行评估。
PLoS One. 2015 Sep 11;10(9):e0137862. doi: 10.1371/journal.pone.0137862. eCollection 2015.
N Engl J Med. 2013 Jun 13;368(24):2277-85. doi: 10.1056/NEJMoa1305584. Epub 2013 May 22.
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Human infection with a novel avian-origin influenza A (H7N9) virus.人感染新型甲型 H7N9 流感病毒。
N Engl J Med. 2013 May 16;368(20):1888-97. doi: 10.1056/NEJMoa1304459. Epub 2013 Apr 11.
5
Sensitivity of influenza rapid diagnostic tests to H5N1 and 2009 pandemic H1N1 viruses.流感快速诊断检测对 H5N1 和 2009 年大流行 H1N1 病毒的敏感性。
J Clin Microbiol. 2010 Aug;48(8):2872-7. doi: 10.1128/JCM.00439-10. Epub 2010 Jun 16.