Hugot Jean-Pierre, Gu Se Hun, Feliu Carlos, Ventur Jacint, Ribas Alexis, Dormion Jerôme, Yanagihara Richard, Nicolas Violaine
UMR CNRS 7205, MNHN, 51, rue Buffon, 75231 Paris cedex, France.
Pacific Center for Emerging Infectious Diseases Research, John A. Burns School of Medicine, University Of Hawaii At Manoa, Honolulu, Hawaii, USA.
Bull Acad Vet Fr. 2014;167(3). doi: 10.4267/2042/54201.
Nova hantavirus (NVAV) was first identified in a single European mole (), captured in Hungary. Analysis of lung tissues from 94 moles captured in France revealed NVAV in 50%. Based on the genetic diversity of the cytochrome mtDNA, moles collected in Poitiers and Bordeaux were more closely related to the Iberian mole (), a species previously assumed to be restricted to the Iberian Peninsula. Several hypotheses are discussed to explain these observations: 1) presence of hitherto unnoticed in southwestern France; 2) existence of an ancient mitochondrial introgression phenomenon between the two species, producing a particular phenotype in some hybrids; 3) existence of a hybrid zone between the two species; and 4) existence of a new species. NVAV was not detected in the southwestern moles, which begs the question of the potential presence of a particular Hantavirus sp. in this population and/or in the Iberian moles.
诺瓦汉坦病毒（NVAV）首次在匈牙利捕获的一只欧洲鼹鼠中被发现。对在法国捕获的94只鼹鼠的肺组织进行分析后发现，其中50%携带NVAV。基于细胞色素线粒体DNA的遗传多样性，在普瓦捷和波尔多收集的鼹鼠与伊比利亚鼹鼠关系更为密切，伊比利亚鼹鼠此前被认为仅分布于伊比利亚半岛。文中讨论了几种假说来解释这些观察结果：1）法国西南部存在迄今未被注意到的[此处原文缺失相关内容]；2）两个物种之间存在古老的线粒体基因渗入现象，在一些杂交后代中产生了特定的表型；3）两个物种之间存在杂交带；4）存在一个新物种。在西南部的鼹鼠中未检测到NVAV，这引发了一个问题，即该种群和/或伊比利亚鼹鼠中是否可能存在特定的汉坦病毒株。
