Chen Denis Guangyin, Law Man-Kay, Lian Yong, Bermak Amine
IEEE Trans Biomed Circuits Syst. 2016 Feb;10(1):186-99. doi: 10.1109/TBCAS.2014.2365515. Epub 2014 Dec 18.
Laser Doppler imaging (LDI) measures particle flows such as blood perfusion by sensing their Doppler shift. This paper is the first of its kind in analyzing the effect of circuit noise on LDI precision which is distinctively different from conventional imaging. Based on this result, it presents a non-correlated-double-sampling (non-CDS) pixel readout scheme along with a high-resolution successive-approximation-register (SAR) analog-to-digital-converter (ADC) with 13.6b effective resolution (ER). Measurement results from the prototype chip in 0.18 μm technology confirm the theoretical analysis and show that the two techniques improve LDI sensing precision by 6.9 dB and 4.4 dB (compared to a 10b ADC) respectively without analog pre-amplification. The sensor's ADC occupies 518 μm×84 μm and is suitable for fast column parallel readout. Its differential non-linearity (DNL), integral non-linearity (INL), and input referred noise are +3.0/-2.8 LSB, +24/-17 LSB, and 110 μVrms respectively, leading to a Figure-of-Merit (FoM) of 23 fJ/state which makes it one of the most energy efficient image sensor ADCs and an order of magnitude better than the best reported LDI system using commercial high-speed image sensors.
激光多普勒成像(LDI)通过检测粒子流的多普勒频移来测量诸如血液灌注等粒子流。本文首次分析了电路噪声对LDI精度的影响,这与传统成像有显著不同。基于此结果,本文提出了一种非相关双采样(non-CDS)像素读出方案以及一种有效分辨率为13.6位(ER)的高分辨率逐次逼近寄存器(SAR)模数转换器(ADC)。采用0.18μm工艺的原型芯片的测量结果证实了理论分析,并表明这两种技术在不进行模拟预放大的情况下,分别将LDI传感精度提高了6.9dB和4.4dB(与10位ADC相比)。该传感器的ADC占用面积为518μm×84μm,适用于快速列并行读出。其差分非线性(DNL)、积分非线性(INL)和输入参考噪声分别为+3.0/-2.8 LSB、+24/-17 LSB和110μVrms,品质因数(FoM)为23 fJ/状态,这使其成为最节能的图像传感器ADC之一,比使用商用高速图像传感器的最佳报道的LDI系统好一个数量级。