Kerasnoudis A, Pitarokoili K, Gold R, Yoon M-S
Department of Neurology, St. Josef Hospital, Ruhr-University of Bochum, Germany.
J Neurol Sci. 2015 Jan 15;348(1-2):211-5. doi: 10.1016/j.jns.2014.12.010. Epub 2014 Dec 11.
The aim of this observational study was to evaluate the applicability of a recently introduced ultrasound score (Bochum ultrasound score; BUS) in distinguishing the chronic inflammatory demyelinating polyneuropathy (CIDP) from the multifocal motor neuropathy (MMN) or the multifocal acquired demyelinating sensory and motor neuropathy (MADSAM).
The BUS underwent prospective evaluation of its applicability in a group of 13 patients (mean age 47.2, SD ± 13.7, 9 women), who were referred to our department between January 2012 and August 2013 with the clinical picture of a chronic symmetrical or asymmetrical sensory/sensorimotor neuropathy.
The cut-off value of ≥ 2 points in the "Bochum ultrasound score" showed a sensitivity of 80% and specificity of 87.5% (PPV=80%, NPV=87.5%) in distinguishing CIDP from MMN or MADSAM.
The BUS seems to allow a reliable distinction of CIDP from multifocal acquired demyelinating polyneuropathies causing predominantly motor nerve dysfunction, such as MMN or MADSAM. Our ultrasound findings indicate a stronger relationship of MADSAM to MMN, than to CIDP.
本观察性研究旨在评估最近引入的超声评分（波鸿超声评分；BUS）在区分慢性炎性脱髓鞘性多发性神经病（CIDP）与多灶性运动神经病（MMN）或多灶性获得性脱髓鞘性感觉和运动神经病（MADSAM）方面的适用性。
对一组13例患者（平均年龄47.2岁，标准差±13.7，9例女性）进行了BUS适用性的前瞻性评估，这些患者在2012年1月至2013年8月期间因慢性对称性或不对称性感觉/感觉运动神经病的临床表现转诊至我科。
“波鸿超声评分”≥2分的截断值在区分CIDP与MMN或MADSAM时，敏感性为80%，特异性为87.5%（阳性预测值=80%，阴性预测值=87.5%）。
BUS似乎能够可靠地区分CIDP与主要导致运动神经功能障碍的多灶性获得性脱髓鞘性多发性神经病，如MMN或MADSAM。我们的超声检查结果表明，MADSAM与MMN的关系比与CIDP的关系更强。
