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蛛网膜下腔出血 7 年后的症状和后果。

Symptoms and consequences of subarachnoid haemorrhage after 7 years.

机构信息

Research Group of Rehabilitation Medicine, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Gothenburg, Sweden.

出版信息

Acta Neurol Scand. 2019 Dec;140(6):429-434. doi: 10.1111/ane.13163. Epub 2019 Oct 1.

DOI:10.1111/ane.13163
PMID:31498424
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7217151/
Abstract

OBJECTIVES

Short-term follow-up studies after a subarachnoid haemorrhage (SAH) have shown impaired cognition, fatigue, depression and anxiety, but less is known regarding long-term consequences. The aim of this study was to investigate health outcomes in persons 7 years after SAH.

MATERIALS AND METHODS

This is a descriptive cohort follow-up study of persons with non-traumatic SAH treated at Sahlgrenska University Hospital, Gothenburg, Sweden. The follow-up was conducted 7 years post-treatment and included home visits using forms and questionnaires about health outcomes; the Barthel Index (BI), modified Rankin Scale (mRS), National Institutes of Health Stroke Scale (NIHSS), Hospital Anxiety and Depression Scale (HADS), Montreal Cognitive Assessment (MoCA) and Multidimensional Fatigue Inventory (MFI).

RESULTS

Seven years post-SAH, 33 persons fulfilled the inclusion criteria, of whom 18 (55%) participated (median age 63 years). Cognitive impairment was present in 11 participants, assessed with the MoCA, where the item of delayed recall was most difficult. The majority (n = 16) were independent in activities of daily living (ADL), and few (n = 3) had physical symptoms according to the NIHSS. However, three participants were free from disability according to the mRS. Nearly, half of the participants had symptoms of anxiety (n = 8). Three had symptoms of depression and more than half experienced fatigue.

CONCLUSION

The physical function and independency in ADL is high among long-term SAH survivors. Despite this, only a few were completely free from disability, and the main problems 7 years after SAH were cognitive impairment and anxiety.

摘要

目的

蛛网膜下腔出血(SAH)后的短期随访研究表明,患者认知功能受损、疲劳、抑郁和焦虑,但对长期后果的了解较少。本研究旨在调查 SAH 后 7 年患者的健康结局。

材料和方法

这是一项对在瑞典哥德堡 Sahlgrenska 大学医院接受治疗的非创伤性 SAH 患者进行的描述性队列随访研究。治疗后 7 年进行随访,通过填写表单和使用有关健康结局的问卷进行家访,包括巴氏指数(BI)、改良 Rankin 量表(mRS)、美国国立卫生研究院卒中量表(NIHSS)、医院焦虑抑郁量表(HADS)、蒙特利尔认知评估量表(MoCA)和多维疲劳量表(MFI)。

结果

SAH 后 7 年,33 名患者符合纳入标准,其中 18 名(55%)患者参与(中位年龄 63 岁)。11 名患者的 MoCA 评估显示存在认知障碍,其中延迟回忆项目最为困难。大多数(n=16)患者日常生活活动(ADL)自理,少数(n=3)患者根据 NIHSS 有躯体症状。然而,根据 mRS,只有 3 名患者无残疾。接近一半的参与者(n=8)有焦虑症状。3 名参与者有抑郁症状,超过一半的参与者有疲劳感。

结论

SAH 长期幸存者的身体功能和 ADL 独立性较高。尽管如此,只有少数患者完全无残疾,SAH 后 7 年的主要问题是认知障碍和焦虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8936/7217151/9138f7424e5d/ANE-140-429-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8936/7217151/337f4081f53d/ANE-140-429-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8936/7217151/9138f7424e5d/ANE-140-429-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8936/7217151/337f4081f53d/ANE-140-429-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8936/7217151/9138f7424e5d/ANE-140-429-g002.jpg

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