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一种用于检测中老年人群轻微认知障碍的筛查工具的有效性

Validity of a screening tool for detecting subtle cognitive impairment in the middle-aged and elderly.

作者信息

Bruce Kathryn M, Robinson Stephen R, Smith Julian A, Yelland Gregory W

机构信息

Department of Surgery (MMC), Monash University, Clayton, VIC, Australia.

School of Health Sciences, RMIT University, Bundoora, VIC, Australia.

出版信息

Clin Interv Aging. 2014 Dec 12;9:2165-76. doi: 10.2147/CIA.S68363. eCollection 2014.

DOI:10.2147/CIA.S68363
PMID:25540581
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4270303/
Abstract

The present study tested 121 middle-aged and elderly community-dwelling individuals on the computer-based Subtle Cognitive Impairment Test (SCIT) and compared their performance with that on several neuropsychological tests. The SCIT had excellent internal consistency, as demonstrated by a high split-half reliability measure (0.88-0.93). Performance on the SCIT was unaffected by the confounding factors of sex, education level, and mood state. Many participants demonstrated impaired performance on one or more of the neuropsychological tests (Controlled Oral Word Association Task, Rey Auditory and Verbal Learning Task, Grooved Pegboard [GP], Complex Figures). Performance on SCIT subtests correlated significantly with performance on many of the neuropsychological subtests, and the best and worst performing quartiles on the SCIT subtest discriminated between good and poor performers on other subtests, collectively indicating concurrent validity of the SCIT. Principal components analysis indicated that SCIT performance does not cluster with performance on most of the other cognitive tests, and instead is associated with decision-making efficacy, and processing speed and efficiency. Thus, the SCIT is responsive to the processes that underpin multiple cognitive domains, rather than being specific for a single domain. Since the SCIT is quick and easy to administer, and is well tolerated by the elderly, it may have utility as a screening tool for detecting cognitive impairment in middle-aged and elderly populations.

摘要

本研究对121名居住在社区的中老年人进行了基于计算机的轻度认知障碍测试(SCIT),并将他们的测试表现与几项神经心理学测试的表现进行了比较。SCIT具有出色的内部一致性,高折半信度测量值(0.88 - 0.93)证明了这一点。SCIT的表现不受性别、教育水平和情绪状态等混杂因素的影响。许多参与者在一项或多项神经心理学测试(受控口语单词联想任务、雷伊听觉言语学习任务、沟槽钉板[GP]、复杂图形)中表现受损。SCIT子测试的表现与许多神经心理学子测试的表现显著相关,并且SCIT子测试中表现最好和最差的四分位数区分了其他子测试中表现好和差的参与者,共同表明了SCIT的同时效度。主成分分析表明,SCIT的表现与大多数其他认知测试的表现不聚类,而是与决策效能以及处理速度和效率相关。因此,SCIT对支持多个认知领域的过程有反应,而不是特定于单个领域。由于SCIT快速且易于实施,并且老年人耐受性良好,它可能作为检测中老年人群认知障碍的筛查工具具有实用价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf7/4270303/e3d9b77fc62f/cia-9-2165Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf7/4270303/a2ec5bbd2ed4/cia-9-2165Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf7/4270303/30782a65f86f/cia-9-2165Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf7/4270303/b5a81407c69e/cia-9-2165Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf7/4270303/e3d9b77fc62f/cia-9-2165Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf7/4270303/a2ec5bbd2ed4/cia-9-2165Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf7/4270303/30782a65f86f/cia-9-2165Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf7/4270303/b5a81407c69e/cia-9-2165Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf7/4270303/e3d9b77fc62f/cia-9-2165Fig4.jpg

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