Massin Sophie, Ventelou Bruno, Nebout Antoine, Verger Pierre, Pulcini Céline
Aix Marseille Université (Aix Marseille School of Economics-SESSTIM UMR 912, Inserm IRD), Marseille, France; Université d'Artois, LEM, UMR 8179, Arras, France.
Aix Marseille Université (Aix Marseille School of Economics-SESSTIM UMR 912, Inserm IRD), Marseille, France; ORS PACA, Observatoire Régional de la Santé Provence-Alpes-Côte d'Azur, Marseille, France; CNRS, U6579 (greqam) , Marseille, France.
Vaccine. 2015 Jan 29;33(5):610-4. doi: 10.1016/j.vaccine.2014.12.038. Epub 2014 Dec 26.
We tested the following hypotheses: (i) risk-averse general practitioners (GPs) are more likely to be vaccinated against influenza; (ii) and risk-averse GPs recommend influenza vaccination more often to their patients. In risk-averse GPs, the perceived benefits of the vaccine and/or the perceived risks of the infectious disease might indeed outweigh the perceived risks of the vaccine.
PATIENTS/METHODS: In 2010-2012, we conducted a cross-sectional survey of a nationwide French representative sample of 1136 GPs. Multivariate analyses adjusted for four stratification variables (age, gender, urban/suburban/rural practice location and annual patient consultations) and for GPs' characteristics (group/solo practice, and occasional practice of alternative medicine, e.g., homeopathy) looked for associations between their risk attitudes and self-reported vaccination behavior. Individual risk attitudes were expressed as a continuous variable, from 0 (risk-tolerant) to 10 (risk-averse).
Overall, 69% of GPs reported that they were very favorable toward vaccination in general. Self-reported vaccination coverage was 78% for 2009/2010 seasonal influenza and 62% for A/H1N1 pandemic influenza. Most GPs (72%) reported recommending the pandemic influenza vaccination to at-risk young adults in 2009, but few than half (42%) to young adults not at risk. In multivariate analyses, risk-averse GPs were more often vaccinated against seasonal (marginal effect=1.3%, P=0.02) and pandemic influenza (marginal effect=1.5%, P=0.02). Risk-averse GPs recommended the pandemic influenza vaccination more often than their more risk-tolerant colleagues to patients without risk factors (marginal effect=1.7%, P=0.01), but not to their at-risk patients and were more favorable toward vaccination in general (marginal effect=1.5%, P=0.04).
Individual risk attitudes may influence GPs' practices regarding influenza vaccination, both for themselves and their patients. Our results suggest that risk-averse GPs may perceive the risks of influenza to outweigh the potential risks related to the vaccine.
我们检验了以下假设:(i)风险规避型全科医生(GPs)更有可能接种流感疫苗;(ii)风险规避型全科医生更频繁地向其患者推荐流感疫苗接种。在风险规避型全科医生中,疫苗的感知益处和/或传染病的感知风险可能确实超过了疫苗的感知风险。
患者/方法:在2010 - 2012年,我们对1136名法国全国代表性样本的全科医生进行了横断面调查。针对四个分层变量(年龄、性别、城市/郊区/农村执业地点和年度患者咨询量)以及全科医生的特征(团体/个体执业,以及顺势疗法等替代医学的偶尔执业情况)进行多变量分析,以寻找他们的风险态度与自我报告的疫苗接种行为之间的关联。个体风险态度用一个连续变量表示,从0(风险容忍)到10(风险规避)。
总体而言,69%的全科医生报告称他们总体上非常支持接种疫苗。2009/2010季节性流感的自我报告接种率为78%,甲型H1N1大流行性流感的接种率为62%。大多数全科医生(72%)报告在2009年向有风险的年轻人推荐了大流行性流感疫苗接种,但向无风险的年轻人推荐的不到一半(42%)。在多变量分析中,风险规避型全科医生更常接种季节性流感疫苗(边际效应 = 1.3%,P = 0.02)和大流行性流感疫苗(边际效应 = 1.5%,P = 0.02)。风险规避型全科医生比风险容忍度更高的同事更频繁地向无风险因素的患者推荐大流行性流感疫苗接种(边际效应 = 1.7%,P = 0.01),但对有风险的患者并非如此,并且总体上对疫苗接种更支持(边际效应 = 1.5%,P = 0.04)。
个体风险态度可能会影响全科医生自身及其患者的流感疫苗接种行为。我们的结果表明,风险规避型全科医生可能认为流感的风险超过了与疫苗相关的潜在风险。