Wang Xiaofeng, Li Shuo, Liu Yu, Ma Changle
College of Life Sciences, Shandong Normal University, Wenhua East Road 88, Jinan, Shandong 250014, China.
College of Life Sciences, Shandong Normal University, Wenhua East Road 88, Jinan, Shandong 250014, China.
Redox Biol. 2015;4:104-8. doi: 10.1016/j.redox.2014.12.006. Epub 2014 Dec 18.
Peroxisomes are ubiquitous organelles present in nearly all eukaryotic cells. Conserved functions of peroxisomes encompass beta-oxidation of fatty acids and scavenging of reactive oxygen species generated from diverse peroxisomal metabolic pathways. Peroxisome content, number, and size can change quickly in response to environmental and/or developmental cues. To achieve efficient peroxisome homeostasis, peroxisome biogenesis and degradation must be orchestrated. We review the current knowledge on redox regulated peroxisome biogenesis and degradation with an emphasis on yeasts and plants.
过氧化物酶体是几乎存在于所有真核细胞中的普遍存在的细胞器。过氧化物酶体的保守功能包括脂肪酸的β-氧化以及清除由各种过氧化物酶体代谢途径产生的活性氧。过氧化物酶体的含量、数量和大小可根据环境和/或发育线索迅速变化。为了实现有效的过氧化物酶体稳态，必须协调过氧化物酶体的生物发生和降解。我们综述了目前关于氧化还原调节的过氧化物酶体生物发生和降解的知识，重点是酵母和植物。
