成人听力障碍：心血管疾病及心血管危险因素的影响

Hearing impairment among adults: the impact of cardiovascular diseases and cardiovascular risk factors.

作者信息

Lohi Venla, Hannula Samuli, Ohtonen Pasi, Sorri Martti, Mäki-Torkko Elina

机构信息

* Institute of Clinical Medicine, Department of Otorhinolaryngology, University of Oulu , Finland.

出版信息

Int J Audiol. 2015 Apr;54(4):265-73. doi: 10.3109/14992027.2014.974112. Epub 2014 Dec 30.

DOI:10.3109/14992027.2014.974112

PMID:25547009

Abstract

OBJECTIVE

To investigate the influence of cardiovascular diseases on hearing impairment (HI) among adults. Furthermore, to seek other potential risk factors for HI, such as smoking, obesity, and socioeconomic class.

DESIGN

A cross-sectional, unscreened, population-based, epidemiological study among adults.

STUDY SAMPLE

The subjects (n = 850), aged 54-66 years, were randomly sampled from the population register. A questionnaire survey, an otological examination, and pure-tone audiometry were performed.

RESULTS

Cardiovascular diseases did not increase the risk for HI in a propensity-score adjusted logistic regression model: OR 1.24, 95% CI 0.79 to 1.96 for HI defined by better ear hearing level (BEHL), and OR 1.48, 95% CI 0.96 to 2.28 for HI defined by worse ear hearing level (WEHL), in the 0.5-4 kHz frequency range. Heavy smoking is a risk factor for HI among men (BEHL: OR 1.96, WEHL: OR 1.88) and women (WEHL: OR 2.4). Among men, obesity (BEHL, OR 1.85) and lower socioeconomic class (BEHL: OR 2.79, WEHL: OR 2.28) are also risk factors for HI.

CONCLUSION

No significant association between cardiovascular disease and HI was found.

摘要

目的

研究心血管疾病对成年人听力障碍（HI）的影响。此外，探寻HI的其他潜在风险因素，如吸烟、肥胖和社会经济阶层。

设计

一项针对成年人的横断面、无筛查、基于人群的流行病学研究。

研究样本

从人口登记册中随机抽取850名年龄在54至66岁之间的受试者。进行了问卷调查、耳科检查和纯音听力测定。

结果

在倾向得分调整的逻辑回归模型中，心血管疾病并未增加HI的风险：在0.5 - 4 kHz频率范围内，以较好耳听力水平（BEHL）定义的HI，比值比（OR）为1.24，95%置信区间（CI）为0.79至1.96；以较差耳听力水平（WEHL）定义的HI，OR为1.48，95%CI为0.96至2.28。重度吸烟是男性（BEHL：OR 1.96，WEHL：OR 1.88）和女性（WEHL：OR 2.4）HI的风险因素。在男性中，肥胖（BEHL，OR 1.85）和较低社会经济阶层（BEHL：OR 2.79，WEHL：OR 2.28）也是HI的风险因素。