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与原发性巨细胞病毒感染相关的短暂性抗磷脂综合征：一例报告及文献综述

Transient antiphospholipid syndrome associated with primary cytomegalovirus infection: a case report and literature review.

作者信息

Nakayama Tsuyoshi, Akahoshi Mitsuteru, Irino Kensuke, Kimoto Yasutaka, Arinobu Yojiro, Niiro Hiroaki, Tsukamoto Hiroshi, Horiuchi Takahiko, Akashi Koichi

机构信息

Department of Clinical Immunology and Rheumatology/Infectious Disease, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

Clinical Education Center, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

出版信息

Case Rep Rheumatol. 2014;2014:271548. doi: 10.1155/2014/271548. Epub 2014 Dec 8.

DOI:10.1155/2014/271548
PMID:25548710
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4274647/
Abstract

Viral infection is known to induce transient autoimmunity in humans. Acute cytomegalovirus (CMV) infection is implicated in occasional thrombosis formation. We here, for the first time, report a 19-year-old female who had an acute CMV infection, leading to a deep venous thrombosis and a pulmonary embolism along with transient appearance of lupus anticoagulant. The pathological role of antiphospholipid antibodies in CMV-mediated thrombosis is discussed.

摘要

已知病毒感染可在人类中诱发短暂性自身免疫。急性巨细胞病毒（CMV）感染偶尔与血栓形成有关。我们在此首次报告一名19岁女性，她患有急性CMV感染，导致深静脉血栓形成和肺栓塞，同时伴有狼疮抗凝物的短暂出现。本文讨论了抗磷脂抗体在CMV介导的血栓形成中的病理作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43da/4274647/a781ca7878b2/CRIRH2014-271548.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43da/4274647/1cbe5a47f835/CRIRH2014-271548.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43da/4274647/a781ca7878b2/CRIRH2014-271548.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43da/4274647/1cbe5a47f835/CRIRH2014-271548.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43da/4274647/a781ca7878b2/CRIRH2014-271548.002.jpg

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Anticardiolipin antibodies-associated stroke in primary CMV infection.原发性巨细胞病毒感染中抗心磷脂抗体相关的中风
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Guidelines on the investigation and management of antiphospholipid syndrome.抗磷脂综合征的调查与管理指南
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Health Sci Rep. 2023 Feb 5;6(2):e1085. doi: 10.1002/hsr2.1085. eCollection 2023 Feb.
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Genetic Predisposition of Anti-Cytomegalovirus Immunoglobulin G Levels and the Risk of 9 Cardiovascular Diseases.抗巨细胞病毒免疫球蛋白 G 水平的遗传易感性与 9 种心血管疾病的风险。
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