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手术椎体骨水泥成形术用于脊柱癌转移的治疗

Surgical vertebral body cementoplasty as spinal cancer metastasis management.

作者信息

N'dri Oka Dominique, Tokpa André, Derou Louis

机构信息

Department of Neurosurgery, Yopougon University Hospital , Abidjan, Cocody , Côte d'Ivoire.

出版信息

Br J Neurosurg. 2015 Jun;29(3):374-9. doi: 10.3109/02688697.2014.994474. Epub 2014 Dec 30.

Abstract

Spinal metastases of cancer are frequent and their treatment strategy remains a problem. The aim of the present paper is to present the technique of cementoplasty and its originality. Spine corporeal cementoplasty techniques were performed in 9 patients with spine metastasis treated at Neurosurgery Department between 2002 and 2005. This series is composed of four women and five men. The average age of patients was 54 years. All patients were admitted for treatment of metastasis of breast carcinoma, metastasis of breast adenocarcinoma (three cases), colon cancer (two cases), pulmonary adenocarcinoma (one case) and melanoma (three cases). Metastasis was located on the cervical spine (3 cases), thoracic spine (4 cases) and lumbar spine (2 cases). No case of cement leaking was observed. In eight patients neurological deficit and pain were decreased. In one patient we noted a persistence of neurological deficit but pain decreased. A post-operative radiological analysis showed good spine stability. Before their death this treatment had improved their quality of life. The technique of surgical cementoplasty described in this paper may be used for a surgical treatment of metastasis and spinal stabilisation. It is an alternative to a palliative treatment of metastasis when it is not possible to perform vertebroplasty.

摘要

癌症脊柱转移很常见,其治疗策略仍是个问题。本文旨在介绍骨水泥成形术技术及其独特之处。2002年至2005年间,在神经外科对9例脊柱转移患者实施了椎体骨水泥成形术。该系列包括4名女性和5名男性。患者的平均年龄为54岁。所有患者均因乳腺癌转移、乳腺腺癌转移(3例)、结肠癌(2例)、肺腺癌(1例)和黑色素瘤(3例)入院治疗。转移位于颈椎(3例)、胸椎(4例)和腰椎(2例)。未观察到骨水泥渗漏病例。8例患者的神经功能缺损和疼痛减轻。1例患者神经功能缺损持续存在,但疼痛减轻。术后影像学分析显示脊柱稳定性良好。在他们去世前,这种治疗改善了他们的生活质量。本文所述的手术骨水泥成形术技术可用于转移瘤的手术治疗和脊柱稳定。当无法进行椎体成形术时,它是转移瘤姑息治疗的一种替代方法。

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