Lee Su-Keon, Lee Seung-Hwan, Yoon Sang-Pil, Lee Young-Tae, Jang Geun, Lim Sang-Youn, Lee Hwan-Mo, Moon Seong-Hwan, Song Kyeong-Seop
Department of Orthopaedic Surgery, Gwangmyeong Sungae Hospital, Gwangmyeong, Korea.
Department of Orthopaedic Surgery, Yonsei University College of Medicine, Seoul, Korea.
Asian Spine J. 2014 Dec;8(6):799-803. doi: 10.4184/asj.2014.8.6.799. Epub 2014 Dec 17.
Retrospective evaluation.
To compare quality of life in postmenopausal women with osteoporotic vertebral fractures (OVFs) who underwent vertebroplasty (VP) or kyphoplasty (KP).
Patient with OVFs who do not respond to conservative treatment can be treated with VP or ballon KP for faster pain relief. There are controversies on which procedure is more effective.
Five hundred twenty-eight postmenopausal women in nationwide hospitals with age of 50 years or older who underwent VP of KP for OVFs were enrolled in this study. Health related quality of life was measured using the European Quality of Life 5 Domains (EQ-5D) and visual analogue scale (VAS).
In the VP group, average EQ-5D dimension was 1.95 in mobility, 1.86 in self care, 2.02 in usual activity, 2.19 in pain, 1.69 in anxiety or depression. In the KP group, average EQ-5D dimension was 1.83 in mobility, 1.78 in self care, 1.98 in usual activity, 2.03 in pain, 1.55 in anxiety or depression. Quality of life of KP group was significantly better than that of the VP group in mobility (p=0.016), pain (p=0.001), and anxiety or depression (p=0.008). Average EQ-5D index of the VP and the KP group was 0.353 (±0.472) and 0.485 (±0.357), respectively. The EQ-5D index of the KP group was significantly (p<0.001) higher than that of the KP group. The difference of VAS between VP and KP group was not statistically significant (p=0.580).
Quality of life in patient with OVFs who underwent KP was significantly better than that of patients who underwent VP.
回顾性评估。
比较接受椎体成形术（VP）或后凸成形术（KP）的绝经后骨质疏松性椎体骨折（OVF）女性的生活质量。
对保守治疗无反应的OVF患者可接受VP或球囊KP治疗以更快缓解疼痛。关于哪种手术更有效存在争议。
528名年龄在50岁及以上、在全国范围内的医院因OVF接受VP或KP的绝经后女性纳入本研究。使用欧洲五维健康量表（EQ-5D）和视觉模拟量表（VAS）测量健康相关生活质量。
在VP组中，EQ-5D各维度平均值在活动能力方面为1.95，自我护理方面为1.86，日常活动方面为2.02，疼痛方面为2.（此处原文有误，应为2.19），焦虑或抑郁方面为1.69。在KP组中，EQ-5D各维度平均值在活动能力方面为1.83，自我护理方面为1.78，日常活动方面为1.98，疼痛方面为2.03，焦虑或抑郁方面为1.55。KP组在活动能力（p = 0.016）、疼痛（p = 0.001）和焦虑或抑郁（p = 0.008）方面的生活质量显著优于VP组。VP组和KP组的平均EQ-5D指数分别为0.353（±0.472）和0.485（±0.357）。KP组的EQ-5D指数显著高于VP组（p < 0.001）。VP组和KP组之间VAS的差异无统计学意义（p = 0.580）。
接受KP的OVF患者的生活质量显著优于接受VP的患者。
