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运用多元统计分析对人参属植物(人参和西洋参)中人参皂苷分布进行代谢组学评估。

Metabolomic evaluation of ginsenosides distribution in Panax genus (Panax ginseng and Panax quinquefolius) using multivariate statistical analysis.

作者信息

Pace Roberto, Martinelli Ernesto Marco, Sardone Nicola, D E Combarieu Eric

出版信息

Fitoterapia. 2015 Mar;101:80-91. doi: 10.1016/j.fitote.2014.12.013. Epub 2015 Jan 3.

Abstract

Ginseng is any one of the eleven species belonging to the genus Panax of the family Araliaceae and is found in North America and in eastern Asia. Ginseng is characterized by the presence of ginsenosides. Principally Panax ginseng and Panax quinquefolius are the adaptogenic herbs and are commonly distributed as health food markets. In the present study high performance liquid chromatography has been used to identify and quantify ginsenosides in the two subject species and the different parts of the plant (roots, neck, leaves, flowers, fruits). The power of this chromatographic technique to evaluate the identity of botanical material and to distinguishing different part of the plants has been investigated with metabolomic technique such as principal component analysis. Metabolomics provide a good opportunity for mining useful chemical information from the chromatographic data set resulting an important tool for quality evaluation of medicinal plants in the authenticity, consistency and efficacy.

摘要

人参是五加科人参属11个物种中的任何一种,分布于北美和东亚。人参的特征是含有人参皂苷。主要的人参属植物有朝鲜人参和西洋参,它们是适应原性草药,在健康食品市场上广泛销售。在本研究中,采用高效液相色谱法对这两个受试物种及其植物不同部位(根、根茎、叶、花、果实)中的人参皂苷进行了鉴定和定量。利用主成分分析等代谢组学技术,研究了这种色谱技术评估植物材料身份和区分植物不同部位的能力。代谢组学为从色谱数据集挖掘有用的化学信息提供了一个很好的机会,成为药用植物真伪、一致性和功效质量评价的重要工具。

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