加利福尼亚州消防员的生物监测：金属与全氟化学品
Biomonitoring in California firefighters: metals and perfluorinated chemicals.
作者信息
Dobraca Dina, Israel Leslie, McNeel Sandra, Voss Robert, Wang Miaomiao, Gajek Ryszard, Park June-Soo, Harwani Suhash, Barley Frank, She Jianwen, Das Rupali
机构信息
From the Environmental Health Investigations Branch (Ms Dobraca, Dr McNeel, Mr Voss, and Dr Das) and Environmental Health Laboratory (Drs Gajek, Barley, and She), California Department of Public Health, Richmond; Center for Occupational and Environmental Health (Dr Israel), University of California, Irvine; and Environmental Chemistry Laboratory (Drs Wang, Park, and Harwani), Department of Toxic Substances Control, California Environmental Protection Agency, Berkeley.
出版信息
J Occup Environ Med. 2015 Jan;57(1):88-97. doi: 10.1097/JOM.0000000000000307.
OBJECTIVE
To assess California firefighters' blood concentrations of selected chemicals and compare with a representative US population.
METHODS
We report laboratory methods and analytic results for cadmium, lead, mercury, and manganese in whole blood and 12 serum perfluorinated chemicals in a sample of 101 Southern California firefighters.
RESULTS
Firefighters' blood metal concentrations were all similar to or lower than the National Health and Nutrition Examination Survey (NHANES) values, except for six participants whose mercury concentrations (range: 9.79 to 13.42 μg/L) were close to or higher than the NHANES reporting threshold of 10 μg/L. Perfluorodecanoic acid concentrations were elevated compared with NHANES and other firefighter studies.
CONCLUSIONS
Perfluorodecanoic acid concentrations were three times higher in this firefighter group than in NHANES adult males. Firefighters may have unidentified sources of occupational exposure to perfluorinated chemicals.
目的
评估加利福尼亚州消防员血液中特定化学物质的浓度，并与美国代表性人群进行比较。
方法
我们报告了南加利福尼亚州101名消防员样本中全血中镉、铅、汞和锰以及12种血清全氟化学物质的实验室方法和分析结果。
结果
消防员血液中的金属浓度均与美国国家健康与营养检查调查（NHANES）的值相似或更低，但有6名参与者的汞浓度（范围：9.79至13.42μg/L）接近或高于NHANES报告阈值10μg/L。与NHANES和其他消防员研究相比，全氟癸酸浓度有所升高。
结论
该消防员群体中的全氟癸酸浓度比NHANES成年男性高两倍。消防员可能存在未被识别的职业性全氟化学物质接触源。
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