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通过静电自组装模板法一步合成用于药物递送纳米系统的磁性中空介孔二氧化硅(MHMS)纳米球。

One-step synthesis of magnetic hollow mesoporous silica (MHMS) nanospheres for drug delivery nanosystems via electrostatic self-assembly templated approach.

作者信息

Liu Fang, Wang Jingnan, Cao Qingyun, Deng Haidong, Shao Guang, Deng David Y B, Zhou Wuyi

机构信息

Institute of Biomaterial, Department of Applied Chemistry, College of Science, South China Agricultural University, Guangzhou 510642, China.

出版信息

Chem Commun (Camb). 2015 Feb 11;51(12):2357-60. doi: 10.1039/c4cc08914f.

Abstract

In this work, yolk-shell structured magnetic hollow mesoporous silica (MHMS) nanospheres with controllable magnetic responsibility, high specific surface area, a huge cavity and ink-bottle type mesopores were successfully synthesized in one-step by an electrostatic self-assembly templated approach. The obtained MHMS nanospheres exhibited low cytotoxicity, excellent biocompatibility and potential application in the biomedical field.

摘要

在本研究中,通过静电自组装模板法一步成功合成了具有可控磁响应性、高比表面积、大空腔和墨水瓶型介孔的蛋黄壳结构磁性中空介孔二氧化硅(MHMS)纳米球。所制备的MHMS纳米球表现出低细胞毒性、优异的生物相容性以及在生物医学领域的潜在应用价值。

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