儿童原发性肾外威尔姆斯瘤

Primary extrarenal Wilms' tumor in children.

作者信息

Broecker B H, Caldamone A A, McWilliams N B, Maurer H, Salzberg A

机构信息

Department of Surgery, Medical College of Virginia, Virginia Commonwealth University, Richmond.

出版信息

J Pediatr Surg. 1989 Dec;24(12):1283-8. doi: 10.1016/s0022-3468(89)80568-8.

DOI:10.1016/s0022-3468(89)80568-8

PMID:2556510

Abstract

We report three additional cases of primary extrarenal Wilms' tumor and review those cases previously documented. Analysis of the location, histopathology, treatment, and survival of these cases supports the following conclusions: Wilms' tumor may occur in an extrarenal location without primary renal involvement and must be included in the differential diagnosis of abdominal, pelvic, and inguinal masses; an extrarenal location supports a more frequent occurrence of ectopic metanephric blastema than was previously recognized or origin of Wilms' tumor from a more primitive mesodermal tissue; and the natural history and prognosis of extrarenal and renal Wilms' tumors appears similar.

摘要

我们报告另外3例原发性肾外Wilms瘤病例，并回顾先前记录的病例。对这些病例的位置、组织病理学、治疗及生存情况进行分析，支持以下结论：Wilms瘤可发生于肾外部位而无原发性肾脏受累，在腹部、盆腔及腹股沟肿块的鉴别诊断中必须考虑到；肾外部位提示异位后肾胚基的发生率比之前认为的更高，或者Wilms瘤起源于更原始的中胚层组织；肾外和肾内Wilms瘤的自然病程及预后似乎相似。