人类首例由塞拉多奴卡菌引起的播散性感染病例。
First case of disseminated infection with Nocardia cerradoensis in a human.
作者信息
Piau Caroline, Kerjouan Mallorie, Le Mouel Marc, Patrat-Delon Solene, Henaux Pierre-Louis, Brun Vanessa, Morin Marie-Pascale, Gautier Philippe, Rodriguez-Nava Veronica, Kayal Samer
机构信息
Medical School, University Rennes 1, Rennes, France IGDR-UMR 6290-CNRS, University Rennes 1, Rennes, France Department of Microbiology, CHU Rennes-Hôpital Pontchaillou, Rennes, France
Medical School, University Rennes 1, Rennes, France Department of Pulmonology, CHU Rennes-Hôpital Pontchaillou, Rennes, France.
出版信息
J Clin Microbiol. 2015 Mar;53(3):1034-7. doi: 10.1128/JCM.02979-14. Epub 2015 Jan 7.
Abstract
Here we report in a human, a renal transplant patient, the first disseminated infection with Nocardia cerradoensis, isolated after a brain biopsy. Species identification was based on 16S rRNA, gyrB, and hsp65 gene analyses. Antibiotic treatment was successful by combining carbapenems and aminoglycosides and then switching to oral trimethoprim-sulfamethoxazole.
摘要
在此，我们报告了一名肾移植患者感染诺卡氏菌属塞拉多ensis的首例播散性感染病例，该菌是在脑部活检后分离出来的。菌种鉴定基于16S rRNA、gyrB和hsp65基因分析。通过联合使用碳青霉烯类抗生素和氨基糖苷类抗生素，然后改用口服复方新诺明进行抗生素治疗，取得了成功。
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