综合医院精神科病房住院精神分裂症患者的心脏危险因素和代谢综合征。
Cardiac risk factors and metabolic syndrome in patients with schizophrenia admitted to a general hospital psychiatric unit.
机构信息
Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, Punjab, India.
Department of Psychiatry, AIIMS, Jodhpur, Rajasthan, India.
出版信息
Indian J Psychiatry. 2014 Oct;56(4):371-6. doi: 10.4103/0019-5545.146520.
OBJECTIVE
The study aimed to evaluate the prevalence of cardiovascular risk (CVR) factors and metabolic syndrome (MS) in patients with schizophrenia.
MATERIALS AND METHODS
By consecutive sampling, 143 patients (of age ≥ 20 years), out of total 159 patients with schizophrenia admitted to the inpatient unit were evaluated for the coronary heart disease (CHD) risk as per Framingham (10-year all CHD events) function/risk equation and systematic coronary risk evaluation (SCORE) - 10-year cardiovascular mortality risk (CMR). Prevalence of MS was estimated by using the consensus definition.
RESULTS
Fifty-two (36.4%) patients fulfilled the criteria for MS. 10-year CHD risk was 1.65%, and 10-year CMR was 1.39%. Compared to females, males had higher Framingham score (1.96 ± 2.74 vs. 1.09 ± 0.41, U value 1987.5*, P < 0.05).
CONCLUSION
Patients of schizophrenia have a high prevalence of MS and CVR factors. Hence, there is a need to screen the patient of schizophrenia for the same and manage the same as early as possible during the course of illness.
目的
本研究旨在评估精神分裂症患者心血管风险（CVR）因素和代谢综合征（MS）的患病率。
材料与方法
通过连续抽样，对 159 名住院精神分裂症患者中的 143 名（年龄≥20 岁）患者，根据 Framingham（10 年所有冠心病事件）函数/风险方程和系统性冠状动脉风险评估（SCORE）-10 年心血管死亡率风险（CMR）评估冠心病（CHD）风险。采用共识定义估计 MS 的患病率。
结果
52 名（36.4%）患者符合 MS 标准。10 年 CHD 风险为 1.65%，10 年 CMR 为 1.39%。与女性相比，男性的 Framingham 评分更高（1.96 ± 2.74 比 1.09 ± 0.41，U 值 1987.5*，P < 0.05）。
结论
精神分裂症患者 MS 和 CVR 因素的患病率较高。因此，有必要对精神分裂症患者进行筛查，并在疾病过程中尽早进行管理。
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