Goldin Philippe, Ramel Wiveka, Gross James
Stanford University.
J Cogn Psychother. 2009 Aug;23(3):242-257. doi: 10.1891/0889-8391.23.3.242.
This study examined the effects of mindfulness-based stress reduction (MBSR) on the brain-behavior mechanisms of self-referential processing in patients with social anxiety disorder (SAD). Sixteen patients underwent functional magnetic resonance imaging while encoding self-referential, valence, and orthographic features of social trait adjectives. Post-MBSR, 14 patients completed neuroimaging. Compared to baseline, MBSR completers showed (a) increased self-esteem and decreased anxiety, (b) increased positive and decreased negative self-endorsement, (c) increased activity in a brain network related to attention regulation, and (d) reduced activity in brain systems implicated in conceptual-linguistic self-view. MBSR-related changes in maladaptive or distorted social self-view in adults diagnosed with SAD may be related to modulation of conceptual self-processing and attention regulation. Self-referential processing may serve as a functional biobehavioral target to measure the effects of mindfulness training.
本研究考察了基于正念的减压疗法（MBSR）对社交焦虑障碍（SAD）患者自我参照加工的脑行为机制的影响。16名患者在对社交特质形容词的自我参照、效价和正字法特征进行编码时接受了功能磁共振成像。MBSR治疗后，14名患者完成了神经影像学检查。与基线相比，完成MBSR治疗的患者表现出：（a）自尊增强、焦虑减轻；（b）积极的自我认同增加、消极的自我认同减少；（c）与注意力调节相关的脑网络活动增加；（d）涉及概念性语言自我观的脑系统活动减少。在被诊断为SAD的成年人中，与MBSR相关的适应不良或扭曲的社交自我观变化可能与概念性自我加工和注意力调节的调节有关。自我参照加工可能作为一个功能性生物行为靶点来衡量正念训练的效果。
