Gowda Giriyanna, Vijayeendra Anagha Manakari, Sarkar Nivedita, Shivalingaiah Anwith Huluvadi, Shah Ankita, Ashwathnarayana Abhiram Gopal, Narayanaswamy Huliraj, Nagaraj Chitra
Department of Community Medicine, Kempegowda Institute of Medical Sciences (KIMS), Bangalore, Rajiv Gandhi University of Health Sciences, Karnataka, India.
Department of Pulmonary Medicine, Kempegowda Institute of Medical Sciences (KIMS), Bangalore, Rajiv Gandhi University of Health Sciences, Karnataka, India.
Indian J Occup Environ Med. 2014 May;18(2):64-7. doi: 10.4103/0019-5278.146893.
The production of silk is a multidimensional and multistep process involving exposure of workers to allergens at work place. The silk allergen has been implicated in the development of bronchial asthma.
To identify the prevalence of occupational asthma (OA) and to identify sensitization to silk allergen and among workers in silk filature units.
A community-based cross-sectional study was conducted in silk filature units of Ramanagara (Silk City) in Karnataka, South India, for a period of 6 months. One hundred and twenty workers of silk filature units who met the inclusion and exclusion criteria were recruited into the study group. For comparison, a control group comprising of 120 individuals not working in silk filature units was constituted. All the subjects were interviewed using the standardized International Union against Tuberculosis and Lung Diseases (IUATLD) Questionnaire and subjected to the skin prick test, which used the extracts of silk allergen.
The study group comprised of 35 males and 85 females, whereas the control group comprised of 58 males and 62 females. The prevalence of occupational asthma among workers in silk filatures was 20.83%. It was observed that 35.83% of those in the study group and 20.83% of those in the control group were found to be sensitive to silk allergen. This difference was statistically significant (χ(2)= 6.64; P < 0.05).
There is a high burden of sensitization to silk allergen and occupational asthma among silk filature workers in South India.
丝绸生产是一个多维度、多步骤的过程，这使得工人在工作场所接触过敏原。丝绸过敏原与支气管哮喘的发病有关。
确定职业性哮喘（OA）的患病率，并确定缫丝单位工人对丝绸过敏原的致敏情况。
在印度南部卡纳塔克邦的拉马纳加拉（丝绸城）的缫丝单位进行了一项基于社区的横断面研究，为期6个月。符合纳入和排除标准的120名缫丝单位工人被招募到研究组。为作比较，组建了一个由120名不在缫丝单位工作的个体组成的对照组。所有受试者均使用标准化的国际防痨和肺部疾病联盟（IUATLD）问卷进行访谈，并接受使用丝绸过敏原提取物的皮肤点刺试验。
研究组包括35名男性和85名女性，而对照组包括58名男性和62名女性。缫丝工人中职业性哮喘的患病率为20.83%。观察发现，研究组中有35.83%的人对丝绸过敏原敏感，对照组中有20.83%的人对丝绸过敏原敏感。这种差异具有统计学意义（χ(2)= 6.64；P < 0.05）。
在印度南部，缫丝工人对丝绸过敏原致敏和患职业性哮喘的负担很重。
