Harindranath N, Prakash O, Subba Rao P V
Ann Allergy. 1985 Sep;55(3):511-5.
A clinical survey in two silk filatures revealed that 36.2% of the persons engaged in the processing of natural silk were suffering from bronchial asthma, while 16.9% of the total subjects had asthma of occupational origin. Skin prick tests using crude silkworm cocoon and pupal allergen extracts revealed that 28.8% of the subjects were sensitive to the silkworm-derived allergens. IgE antibodies specific to both cocoon and pupal allergens were demonstrable by RAST in the sera of patients with positive skin reactions and occupational asthma.
在两家缫丝厂进行的一项临床调查显示，从事天然丝加工的人员中有36.2%患有支气管哮喘，而所有受试者中有16.9%患有职业性哮喘。使用粗蚕茧和蚕蛹过敏原提取物进行的皮肤点刺试验显示，28.8%的受试者对蚕源性过敏原敏感。通过放射变应原吸附试验（RAST）可在皮肤反应阳性和职业性哮喘患者的血清中检测到针对茧和蛹过敏原的IgE抗体。
