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眼像放大对 Spectralis 频域光学相干断层扫描长度的影响。

The effects of ocular magnification on Spectralis spectral domain optical coherence tomography scan length.

机构信息

Applied Vision Research Centre, The Henry Wellcome Laboratories for Vision Sciences, City University London, Northampton Square, London, EC1V 0HB, UK,

出版信息

Graefes Arch Clin Exp Ophthalmol. 2015 May;253(5):733-8. doi: 10.1007/s00417-014-2915-9. Epub 2015 Jan 10.

Abstract

PURPOSE

The purpose of this study was to assess the effects of incorporating individual ocular biometry measures of corneal curvature, refractive error, and axial length on scan length obtained using Spectralis spectral domain optical coherence tomography (SD-OCT).

METHODS

Two SD-OCT scans were acquired for 50 eyes of 50 healthy participants, first using the Spectralis default keratometry (K) setting followed by incorporating individual mean-K values. Resulting scan lengths were compared to predicted scan lengths produced by image simulation software, based on individual ocular biometry measures including axial length.

RESULTS

Axial length varied from 21.41 to 29.04 mm. Spectralis SD-OCT scan lengths obtained with default-K ranged from 5.7 to 7.3 mm, and with mean-K from 5.6 to 7.6 mm. We report a stronger correlation of simulated scan lengths incorporating the subject's mean-K value (ρ = 0.926, P < 0.0005) compared to Spectralis default settings (ρ = 0.663, P < 0.0005).

CONCLUSIONS

Ocular magnification appears to be better accounted for when individual mean-K values are incorporated into Spectralis SD-OCT scan acquisition versus using the device's default-K setting. This must be considered when taking area measurements and lateral measurements parallel to the retinal surface.

摘要

目的

本研究旨在评估在 Spectralis 频域光学相干断层扫描(SD-OCT)中纳入角膜曲率、屈光不正和眼轴的个体眼生物测量值对扫描长度的影响。

方法

对 50 名健康参与者的 50 只眼进行了两次 SD-OCT 扫描,第一次使用 Spectralis 默认角膜曲率(K)设置,然后纳入个体平均 K 值。将获得的扫描长度与基于包括眼轴在内的个体眼生物测量值的图像模拟软件生成的预测扫描长度进行比较。

结果

眼轴长度从 21.41 毫米到 29.04 毫米不等。使用默认-K 的 Spectralis SD-OCT 扫描长度范围为 5.7 毫米到 7.3 毫米,使用平均-K 的扫描长度范围为 5.6 毫米到 7.6 毫米。我们报告了纳入受试者平均 K 值的模拟扫描长度相关性更强(ρ=0.926,P<0.0005),而 Spectralis 默认设置的相关性较弱(ρ=0.663,P<0.0005)。

结论

在 Spectralis SD-OCT 扫描采集时纳入个体平均 K 值,而不是使用设备的默认 K 设置,似乎可以更好地解释眼放大率。在进行面积测量和与视网膜表面平行的横向测量时,必须考虑这一点。

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