Alegret Josep M, Beltrán-Debón Raúl, La Gerche Andre, Franco-Bonafonte Luis, Rubio-Pérez Francisco, Calvo Nahum, Montero Manuel
Grup de Recerca Cardiovascular, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Av. del Dr. Josep Laporte 2, 43204, Reus, Spain,
Eur J Appl Physiol. 2015 Jun;115(6):1195-203. doi: 10.1007/s00421-015-3101-4. Epub 2015 Jan 10.
The acute effect of static exercise on the global dynamics of the cardiovascular system is poorly understood. The use of cardiovascular magnetic resonance (CMR) may be useful for evaluating this effect.
A total of 12 healthy individuals underwent CMR imaging at rest and while performing a maximal sustained static exercise (weight elevation with both legs). We analyzed the effects on left and right ventricular function, ascending aorta dynamics, and venous capacitance using standard cine and phase-contrast sequences.
We observed excellent reproducibility in the measurements of the images obtained at rest as well as during static exercise. During exercise, we observed reduced left (-35 ± 8 %, p < 0.001) and right (-44 ± 9 %, p < 0.001) ventricle end-diastolic volumes, reduced left (-35 ± 16 %, p < 0.001) and right (-43 ± 8 %, p < 0.001) ventricle end-systolic volumes (both with a significantly greater reduction in the right ventricle), a reduced superior vena cava cross-sectional area (-20 ± 17 %, p = 0.003), and increased left ventricle wall thickness. We estimated that there was an increase in left ventricle contractility. There were no significant changes in the left and right ventricular ejection fractions. During exercise, we noted a tendency toward decreased aortic distensibility and a reduction of ascending aorta systolic expansion.
In healthy individuals, an acute maximal static exercise produced a reduction in the left ventricle, right ventricle, and superior vena cava volumes as well as signs of increased aortic stiffness without increasing left ventricular systolic wall stress. CMR is feasible and useful in evaluating the hemodynamic effects of static exercise.
静态运动对心血管系统整体动力学的急性影响尚不清楚。使用心血管磁共振成像（CMR）可能有助于评估这种影响。
共有12名健康个体在静息状态下以及进行最大持续静态运动（双腿抬高负重）时接受了CMR成像。我们使用标准电影序列和相位对比序列分析了对左、右心室功能、升主动脉动力学和静脉容量的影响。
我们观察到静息状态下以及静态运动期间获得的图像测量具有出色的可重复性。运动期间，我们观察到左心室舒张末期容积减少（-35±8%，p<0.001），右心室舒张末期容积减少（-44±9%，p<0.001），左心室收缩末期容积减少（-35±16%，p<0.001），右心室收缩末期容积减少（-43±8%，p<0.001）（右心室减少幅度明显更大），上腔静脉横截面积减少（-20±17%，p=0.003），左心室壁厚度增加。我们估计左心室收缩性增加。左、右心室射血分数无显著变化。运动期间，我们注意到主动脉扩张性有降低趋势，升主动脉收缩期扩张减少。
在健康个体中，急性最大静态运动导致左心室、右心室和上腔静脉容积减少，以及主动脉僵硬度增加的迹象，而未增加左心室收缩期壁应力。CMR在评估静态运动的血流动力学影响方面是可行且有用的。
