Department of Medicine, John H Stroger Hospital of Cook County, Chicago, IL, USA.
Department of Medicine, John H Stroger Hospital of Cook County, Chicago, IL, USA. ; Department of Medicine, Rush University Medical Center, Chicago, IL, USA.
J Gastric Cancer. 2014 Dec;14(4):275-8. doi: 10.5230/jgc.2014.14.4.275. Epub 2014 Dec 26.
Gastric cancer is rare during pregnancy, and often advanced upon presentation. A Krukenberg tumor presents a diagnostic and therapeutic challenge in the pregnant patient. We present a case of a 38-year-old woman at 22 weeks' gestation who presented with worsening epigastric pain, and was found to have a left pelvic mass on ultrasound, which was confirmed by magnetic resonance imaging. She went into active labor and delivered a viable infant via vaginal delivery. An exploratory laparotomy revealed a large mass originating from her left ovary and diffuse thickening of the lesser curvature of the stomach. Frozen section investigation revealed the presence of signet cell adenocarcinoma. Subsequent upper endoscopy showed linitis plastica, while biopsy confirmed the presence of adenocarcinoma. In conclusion, the occurrence of gastric cancer in pregnancy is rare despite extremely common symptoms. The management poses a challenge because of the need for early treatment, and the continuation of the pregnancy.
胃癌在怀孕期间较为罕见,且通常在就诊时已处于晚期。在妊娠患者中,克鲁肯贝格瘤(Krukenberg 肿瘤)的诊断和治疗颇具挑战。我们报告了一例 38 岁女性病例,她在妊娠 22 周时出现上腹疼痛加剧,并在超声检查时发现左侧盆腔肿块,进一步的磁共振成像(MRI)证实了这一结果。她进入活跃分娩期,并经阴道分娩产下了一个存活的婴儿。剖腹探查术显示,一个源自左侧卵巢的巨大肿块,以及胃小弯弥漫性增厚。冷冻切片检查显示存在印戒细胞腺癌。随后的上内窥镜检查显示皮革胃,活检证实存在腺癌。总之,尽管症状极为常见,但胃癌在怀孕期间的发生率仍然较低。由于需要早期治疗和继续妊娠,因此其管理颇具挑战。