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老年人肌肉减少症的方法、诊断标准、临界点及患病率。

Methods, diagnostic criteria, cutoff points, and prevalence of sarcopenia among older people.

作者信息

Pagotto Valéria, Silveira Erika Aparecida

机构信息

Nursing School, Federal University of Goiás, 227 Street, Block 68, s/n, Setor Leste Universitário, 74605-080 Goiânia, GO, Brazil.

School of Medicine, Federal University of Goiás, Postgraduate Program in Health Sciences, 235 Street s/n, Setor Leste Universitário, 74605-020 Goiânia, GO, Brazil.

出版信息

ScientificWorldJournal. 2014;2014:231312. doi: 10.1155/2014/231312. Epub 2014 Dec 17.

Abstract

AIM

To identify methods, index, diagnostic criteria, and corresponding cutoff points used to estimate the prevalence of sarcopenia in older people in different countries.

METHODS

A systematic review was carried out in accordance with PRISMA Statement. The search encompassed the MEDLINE and LILACS databases and was executed during March 2012 using the keyword sarcopenia.

RESULTS

A total of 671 studies were identified by the search strategy, and 30 meet all inclusion criteria. Specifically for dual-X-ray absorptiometry, prevalence ranged from 2.2% to 95% in men and from 0.1% to 33.9% in women. For bioelectrical impedance analysis, the range was from 6.2% to 85.4% in men and 2.8% to 23.6% in women. Regarding anthropometric and computed tomography, prevalence rates were, respectively, 14.1% and 55.9%.

CONCLUSIONS

Heterogeneity in prevalence of sarcopenia was identified, due to diagnostic method choice, cutoff points, and, characteristics of the population as well as reference population. These factors should be considered in research designs to enable comparison and validation of results. Despite the limitations of most studies that indicated high prevalence rates, the results indicate the need for early detection of this syndrome.

摘要

目的

确定用于估计不同国家老年人肌少症患病率的方法、指标、诊断标准及相应切点。

方法

按照PRISMA声明进行系统评价。检索范围包括MEDLINE和LILACS数据库,于2012年3月使用关键词“肌少症”进行检索。

结果

检索策略共识别出671项研究,其中30项符合所有纳入标准。具体而言,对于双能X线吸收法,男性患病率为2.2%至95%,女性为0.1%至33.9%。对于生物电阻抗分析,男性范围为6.2%至85.4%,女性为2.8%至23.6%。关于人体测量法和计算机断层扫描,患病率分别为14.1%和55.9%。

结论

由于诊断方法的选择、切点、人群特征以及参考人群的不同,肌少症患病率存在异质性。在研究设计中应考虑这些因素,以便结果能够进行比较和验证。尽管大多数研究存在局限性且显示患病率较高,但结果表明需要早期检测该综合征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c532/4280495/ca6ea175566c/TSWJ2014-231312.001.jpg

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