Freese Eric C, Gist Nicholas H, Acitelli Rachelle M, McConnell Whitni J, Beck Catherine D, Hausman Dorothy B, Murrow Jonathan R, Cureton Kirk J, Evans Ellen M
Department of Kinesiology, University of Georgia, Athens, Georgia;
Department of Kinesiology, University of Georgia, Athens, Georgia; Department of Physical Education, United States Military Academy, West Point, New York;
J Appl Physiol (1985). 2015 Apr 1;118(7):872-9. doi: 10.1152/japplphysiol.00380.2014. Epub 2015 Jan 15.
Individuals diagnosed with the metabolic syndrome (MetS) exhibit elevated postprandial lipemia (PPL). The aims of this investigation were to determine 1) if an acute bout of sprint interval training (SIT) attenuates PPL; and 2) if the attenuation of PPL following 6 wk of SIT is magnified compared with a single session of SIT prior to training in women at-risk for MetS (n = 45; 30-65 yr). Women were randomized to SIT (n = 22) or a nonexercise control (n = 23; CON) for 6 wk. Postprandial responses to a high-fat meal challenge (HFMC) were assessed in the CON group before (B-HFMC) and after (Post-HFMC) without prior exercise and in the SIT group at baseline (B-HFMC) without prior exercise, after an acute bout of SIT (four 30-s all-out sprints with 4-min recovery) prior to (Pre-HFMC), and after the 6-wk intervention (Post-HFMC). Responses to the HFMC were assessed by collecting venous blood samples in the fasted state and at 0, 30, 60, 120, and 180 min postprandial. Compared with baseline, an acute bout of SIT before (Pre-HFMC) and after the 6-wk intervention (Post-HFMC) significantly attenuated fasted TG (P < 0.05; 16.6% and 12.3%, respectively) and postprandial area under the curve (13.1% and 9.7%, respectively; tAUC) TG responses. There was no difference in fasted or tAUC TG responses between Pre-HFMC and Post-HFMC. SIT is an effective mode of exercise to reduce fasted and postprandial TG concentrations in women at-risk for MetS. Six weeks of SIT does not magnify the attenuation of PPL in response to a single session of SIT.
被诊断患有代谢综合征（MetS）的个体表现出餐后血脂升高（PPL）。本研究的目的是确定：1）一次急性短跑间歇训练（SIT）是否能减轻PPL；2）与在有患MetS风险的女性（n = 45；30 - 65岁）训练前进行一次SIT相比，6周SIT后PPL的减轻是否会更大。女性被随机分为SIT组（n = 22）或非运动对照组（n = 23；CON），为期6周。在CON组未进行运动前（B - HFMC）和运动后（Post - HFMC）以及SIT组基线时（B - HFMC）未进行运动、在一次急性SIT（四次30秒全力冲刺，恢复4分钟）前（Pre - HFMC）和6周干预后（Post - HFMC）评估对高脂餐挑战（HFMC）的餐后反应。通过在空腹状态以及餐后0、30、60、120和180分钟采集静脉血样来评估对HFMC的反应。与基线相比，一次急性SIT前（Pre - HFMC）和6周干预后（Post - HFMC）显著降低了空腹甘油三酯（P < 0.05；分别降低16.6%和12.3%）以及餐后曲线下面积（分别降低13.1%和9.7%；tAUC）甘油三酯反应。Pre - HFMC和Post - HFMC之间空腹或tAUC甘油三酯反应无差异。SIT是降低有患MetS风险女性空腹和餐后甘油三酯浓度的有效运动方式。6周的SIT不会增强单次SIT对PPL的减轻作用。
