Maes Iris H L, Delespaul Philippe A E G, Peters Madelon L, White Mathew P, van Horn Yvette, Schruers Koen, Anteunis Lucien, Joore Manuela
Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Center, Maastricht, The Netherlands; Adelante Centre of Expertise in Rehabilitation and Audiology, Hoensbroek, The Netherlands; Department of Clinical Psychological Science, Maastricht University, Maastricht, The Netherlands.
Mondriaan Mental Health Care Trust, South Limburg, The Netherlands; School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.
Value Health. 2015 Jan;18(1):44-51. doi: 10.1016/j.jval.2014.10.003.
To explore the potential value of obtaining momentary, instead of retrospective, accounts of the description and valuation of a person's own health-related quality of life (HRQOL).
Momentary HRQOL was examined with the experience sampling method (ESM) in 139 participants from four different samples. The ESM consists of a so-called beep questionnaire that was administered 10 times a day by an electronic device. Feasibility was determined by assessing willingness to participate in the study and by analyzing the percentage of dropouts and the number of completed beep questionnaires. Multilevel analysis was used to investigate the relation between momentary HRQOL and momentary feelings and symptoms. The relation between momentary outcomes and the EuroQol visual analogue scale was investigated with a multiple regression model.
The overall participation rate was low, but there were no dropouts and the number of completed beeps was comparable to that in other studies. Multilevel analysis showed that feelings and symptoms were significant predictors of momentary HRQOL. The strength of these relations differed among three patient groups and a population-based sample. The EuroQol visual analogue scale was not predicted by momentary feelings and symptoms.
We can conclude that the use of the ESM to measure accounts of the momentary experience of health in different populations is feasible. Retrospective measures may provide a biased account of the impact of health problems in the daily lives of people who are affected. Moreover, the bias may be different in different conditions.
探讨获取个人自身健康相关生活质量（HRQOL）的即时描述和评估，而非回顾性描述和评估的潜在价值。
采用经验抽样法（ESM）对来自四个不同样本的139名参与者的即时HRQOL进行了研究。ESM包括一份所谓的蜂鸣问卷，由电子设备每天发放10次。通过评估参与研究的意愿、分析退出率和完成的蜂鸣问卷数量来确定可行性。采用多水平分析来研究即时HRQOL与即时感受和症状之间的关系。使用多元回归模型研究即时结果与欧洲五维度健康量表视觉模拟评分之间的关系。
总体参与率较低，但没有参与者退出，完成的蜂鸣问卷数量与其他研究相当。多水平分析表明，感受和症状是即时HRQOL的重要预测因素。这些关系的强度在三个患者组和一个基于人群的样本中有所不同。即时感受和症状无法预测欧洲五维度健康量表视觉模拟评分。
我们可以得出结论，使用ESM来测量不同人群的即时健康体验是可行的。回顾性测量可能会对受影响人群日常生活中健康问题所产生的影响提供有偏差的描述。此外，不同情况下偏差可能有所不同。
