O'Rourke K I, Perryman L E, McGuire T C
Department of Veterinary Microbiology and Pathology, Washington State University, Pullman 99164.
Vet Immunol Immunopathol. 1989 Nov 30;23(1-2):41-9. doi: 10.1016/0165-2427(89)90108-6.
Antibody responses in horses with equine infectious anemia virus (EIAV) were examined to determine their cross-neutralizing capacity. Antibodies induced by infection with any of six biologically cloned variants of EIAV cross-neutralized multiple variants from the group. Anti-EIAV antibody was found in both the IgG and IgG(T) subclasses in plasmas with virus-neutralizing activity and the majority of antiviral antibody was of the IgG(T) subclass. Depletion of IgG(T) did not increase the neutralization indexes of either neutralizing or non-neutralizing plasma samples.
对感染马传染性贫血病毒（EIAV）的马匹的抗体反应进行了检测，以确定其交叉中和能力。感染EIAV六种生物学克隆变体中任何一种所诱导的抗体可交叉中和该组中的多种变体。在具有病毒中和活性的血浆中，IgG和IgG(T)亚类中均发现了抗EIAV抗体，且大多数抗病毒抗体属于IgG(T)亚类。去除IgG(T)并没有提高中和或非中和血浆样本的中和指数。
