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采用反相高效液相色谱分析法对印度西高止山脉特有的五种獐牙菜属植物中的三种五环三萜进行定量测定。

Quantitative determination of three pentacyclic triterpenes from five Swertia L. species endemic to Western Ghats, India, using RP-HPLC analysis.

作者信息

Kshirsagar Parthraj R, Pai Sandeep R, Nimbalkar Mansingraj S, Gaikwad Nikhil B

机构信息

a Laboratory of Cytogenetics and Plant Breeding, Department of Botany , Shivaji University , Kolhapur 416 004 , MS , India.

出版信息

Nat Prod Res. 2015;29(19):1783-8. doi: 10.1080/14786419.2015.1004174. Epub 2015 Jan 23.

DOI:10.1080/14786419.2015.1004174
PMID:25613495
Abstract

Aim of this study was to identify pentacyclic triterpenoids betulinic acid (BA), oleanolic acid (OA) and ursolic acid (UA) from five Swertia species endemic to Western Ghats, which are used as substitutes as well as adulterants to Swertia chirayita. Our results indicate that the concentration of active compound vary largely among and within the species from different localities. OA was found in a higher amount in all species compared to BA and UA. From the results, it was clear that BA, OA and UA are present in the endemic species collected from Western Ghats, thus advocating the use of these species as alternate sources to S. chirayita. This in due course may release pressure of exploitation from natural resources of S. chirayita and help to bring it out from an endangered category from conservation point of view.

摘要

本研究的目的是从西高止山脉特有的五种獐牙菜属植物中鉴定五环三萜类化合物桦木酸(BA)、齐墩果酸(OA)和熊果酸(UA),这些植物被用作印度獐牙菜的替代品和掺假物。我们的结果表明,活性化合物的浓度在来自不同地区的物种之间以及物种内部差异很大。与BA和UA相比,所有物种中OA的含量都更高。从结果来看,很明显从西高止山脉采集的特有物种中存在BA、OA和UA,因此提倡将这些物种用作印度獐牙菜的替代来源。这在适当的时候可能会减轻对印度獐牙菜自然资源的开发压力,并有助于从保护角度将其从濒危类别中解救出来。

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