Division of Rheumatology, Montefiore Medical Center, 111 East 210th Street, Bronx, NY, 10467-2490, USA,
Curr Rheumatol Rep. 2015 Feb;17(2):5. doi: 10.1007/s11926-014-0479-7.
Autoimmune thyroiditis (ATD) is generally regarded as a classic example of single organ autoimmunity with a high association with endocrine thyroid disorders. However, it is closely associated with several autoimmune diseases including rheumatologic syndromes and has long been known to have several rheumatic manifestations particularly in association with hypothyroidism. More recently, it has also been implicated in rheumatologic syndromes in the absence of hypothyroidism or subclinical hypothyroidism. There is also an emerging body of evidence that ATD is highly linked to chronic generalized pain syndromes including fibromyalgia. This review examines the rheumatic symptoms of ATD described in the current literature and discusses the clinical relevance of ATD in general rheumatology.
自身免疫性甲状腺炎（ATD）通常被认为是单一器官自身免疫的经典范例，与内分泌甲状腺疾病高度相关。然而，它与几种自身免疫性疾病密切相关，包括风湿性综合征，并且长期以来一直被认为具有多种风湿表现，特别是与甲状腺功能减退症有关。最近，即使在没有甲状腺功能减退症或亚临床甲状腺功能减退症的情况下，它也与风湿性综合征有关。也有越来越多的证据表明 ATD 与慢性全身性疼痛综合征（包括纤维肌痛）高度相关。这篇综述检查了当前文献中描述的 ATD 的风湿症状，并讨论了 ATD 在一般风湿病学中的临床相关性。
