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采用下腹皮下入路对外阴癌患者行视频内镜腹股沟淋巴结清扫术的初步经验。

Preliminary experience of performing a video endoscopic inguinal lymphadenectomy using a hypogastric subcutaneous approach in patients with vulvar cancer.

作者信息

Wang He, Li Li, Yao Desheng, Li Fei, Zhang Jieqing, Yang Zhijun

机构信息

Department of Gynecologic Oncology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.

出版信息

Oncol Lett. 2015 Feb;9(2):752-756. doi: 10.3892/ol.2014.2757. Epub 2014 Dec 2.

Abstract

To evaluate the feasibility and surgical outcome of video endoscopic inguinal lymphadenectomy (VEIL) using a hypogastric subcutaneous approach, 21 patients with vulvar cancer who underwent this procedure were included in the present study. Between December 2010 and March 2013, 21 consecutive patients with vulvar cancer underwent radical vulvectomy and VEIL using a hypogastric subcutaneous approach. The intraoperative and post-operative results and follow-up data were retrospectively analyzed. No intraoperative complications occurred. The mean duration of surgery for the endoscopic inguinal lymphadenectomies was 130 min (range, 80-180 min), with a mean estimated blood loss of 103 ml (range, 30-350 ml). The mean lymph node yield was 15 (range, 10-22 lymph nodes). The suction drains were removed after a mean duration of 7 days (range, 5-11 days). No skin-related complications were observed in the groin region and a lymphocele was only observed in 1/21 (4.8%) patients. After a mean follow-up period of 17 months (range, 3-31 months), recurrence was found in only one patient. All the patients were alive at the time of publication. Based on our preliminary experience, performing VEIL using a hypogastric subcutaneous approach is a safe and feasible technique for patients with vulvar cancer. These results indicate that this surgical technique may decrease the post-operative morbidity of lymphadenectomy without compromising the therapeutic efficacy. Future prospective studies with a greater sample size and a longer duration of follow-up are required.

摘要

为评估采用下腹皮下入路的视频内镜腹股沟淋巴结切除术(VEIL)的可行性及手术效果,本研究纳入了21例行该手术的外阴癌患者。2010年12月至2013年3月期间,21例连续的外阴癌患者接受了根治性外阴切除术及采用下腹皮下入路的VEIL。对术中及术后结果和随访数据进行了回顾性分析。术中未发生并发症。内镜腹股沟淋巴结切除术的平均手术时间为130分钟(范围80 - 180分钟),平均估计失血量为103毫升(范围30 - 350毫升)。平均淋巴结收获量为15个(范围10 - 22个淋巴结)。引流管平均在7天(范围5 - 11天)后拔除。腹股沟区未观察到与皮肤相关的并发症,仅1/21(4.8%)的患者出现了淋巴囊肿。平均随访17个月(范围3 - 31个月)后,仅1例患者复发。在发表时所有患者均存活。基于我们的初步经验,对于外阴癌患者,采用下腹皮下入路进行VEIL是一种安全可行的技术。这些结果表明,该手术技术可降低淋巴结切除术后的发病率,且不影响治疗效果。未来需要进行更大样本量和更长随访时间的前瞻性研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d597/4301472/72069e001efe/OL-09-02-0752-g00.jpg

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