Meng Lei, Wang Jin, Fang Song-Hua
Lei Meng, Song-Hua Fang, Department of Radiology, Sir Run Run Shaw Hospital, Sir Run Run Shaw Institute of Clinical Medicine of Zhejiang University, Hangzhou 310016, Zhejiang Province, China.
World J Gastroenterol. 2015 Jan 21;21(3):1036-9. doi: 10.3748/wjg.v21.i3.1036.
Paraganglioma is a rare tumor of paraganglia, derived from neural crest cells in sympathetic or parasympathetic ganglions. Primary paraganglioma originating from the pancreas is rare. We report two patients with paraganglioma in the head of the pancreas, in whom computed tomography showed a sharply marginated, hypervascular tumor with cystic areas. Significant intratumoral vessels and early contrast filling of the draining veins from the mass were not found. Although the pancreatic paraganglioma was located at the pancreatic head, the bile ducts often revealed no dilation, and sometimes the main pancreatic duct was mildly dilated. These findings are helpful in differentiating pancreatic paraganglioma from other pancreatic neoplasms. It is often difficult to distinguish between nonfunctional pancreatic paragangliomas and pancreatic endocrine tumors. In many reports,pancreatic paragangliomas show the retroperitoneal extension of a paraganglioma into the pancreas rather than a true pancreatic neoplasm. In surgical treatment, we could select simple excision of the tumor rather than radical surgery.
副神经节瘤是一种罕见的副神经节肿瘤，起源于交感神经或副交感神经节中的神经嵴细胞。原发性胰腺副神经节瘤很罕见。我们报告了两名胰腺头部副神经节瘤患者，计算机断层扫描显示肿瘤边界清晰、血供丰富，并有囊性区域。未发现肿瘤内有明显血管及肿块引流静脉的早期造影剂充盈。尽管胰腺副神经节瘤位于胰头，但胆管通常无扩张，有时主胰管轻度扩张。这些发现有助于胰腺副神经节瘤与其他胰腺肿瘤的鉴别。非功能性胰腺副神经节瘤与胰腺内分泌肿瘤常难以区分。在许多报道中，胰腺副神经节瘤表现为副神经节瘤向胰腺的腹膜后延伸，而非真正的胰腺肿瘤。在手术治疗中，我们可以选择单纯肿瘤切除而非根治性手术。
