2012年智利的脑膜炎奈瑟菌ST-11克隆复合体
Neisseria meningitidis ST-11 clonal complex, Chile 2012.
作者信息
Araya Pamela, Fernández Jorge, Del Canto Felipe, Seoane Mabel, Ibarz-Pavón Ana B, Barra Gisselle, Pidal Paola, Díaz Janepsy, Hormazábal Juan C, Valenzuela María T
出版信息
Emerg Infect Dis. 2015 Feb;21(2):339-41. doi: 10.3201/eid2102.140746.
Abstract
Serogroup W Neisseria meningitidis was the main cause of invasive meningococcal disease in Chile during 2012. The case-fatality rate for this disease was higher than in previous years. Genotyping of meningococci isolated from case-patients identified the hypervirulent lineage W:P1.5,2:ST-11, which contained allele 22 of the fHbp gene.
摘要
2012年期间，W群脑膜炎奈瑟菌是智利侵袭性脑膜炎球菌病的主要病因。该疾病的病死率高于前几年。对从病例患者中分离出的脑膜炎球菌进行基因分型，确定了高毒力谱系W:P1.5,2:ST-11，其包含fHbp基因的22等位基因。
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