OPTN/SRTR 2013 年年度数据报告：肝脏。

OPTN/SRTR 2013 Annual Data Report: liver.

机构信息

Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN; Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA.

出版信息

Am J Transplant. 2015 Jan;15 Suppl 2:1-28. doi: 10.1111/ajt.13197.

DOI:10.1111/ajt.13197

PMID:25626341

Abstract

During 2013, 10,479 adult candidates were added to the liver transplant waiting list, compared with 10,185 in 2012; 5921 liver transplants were performed, and 211 of the transplanted organs were from living donors. As of December 31, 2013, 15,027 candidates were registered on the waiting list, including 12,407 in active status. The most significant change in allocation policy affecting liver waitlist trends in 2013 was the Share 35 policy, whereby organs from an entire region are available to candidates with model for end-stage liver disease scores of 35 or higher. Median waiting time for such candidates decreased dramatically, from 14.0 months in 2012 to 1.4 months in 2013, but the effect on waitlist mortality is unknown. The number of new active pediatric candidates added to the liver transplant waiting list increased to 693 in 2013. Transplant rates were highest for candidates aged younger than 1 year (275.6 per 100 waitlist years) and lowest for candidates aged 11 to 17 years (97.0 per 100 waitlist years). Five-year graft survival was 71.7% for recipients aged younger than 1 year, 74.9% for ages 1 to 5 years, 78.9% ages 6 to 10 years, and 77.4% for ages 11 to 17 years.

摘要

2013 年，有 10479 名成年候选者被添加到肝移植等候名单中，而 2012 年为 10185 名；进行了 5921 例肝移植，其中 211 例器官来自活体供者。截至 2013 年 12 月 31 日，有 15027 名候选者在等候名单上登记，其中 12407 名处于活跃状态。2013 年影响肝等候名单趋势的分配政策的最大变化是 Share 35 政策，根据该政策，整个地区的器官都可用于终末期肝病模型评分达到 35 或更高的候选者。此类候选者的中位等候时间从 2012 年的 14.0 个月急剧下降到 2013 年的 1.4 个月，但对等候名单死亡率的影响尚不清楚。2013 年，新增的活跃儿科候选者人数增加到 693 人。肝移植等候名单中年龄在 1 岁以下的候选者的移植率最高（每 100 个等候名单年 275.6 例），年龄在 11 至 17 岁的候选者的移植率最低（每 100 个等候名单年 97.0 例）。年龄在 1 岁以下的受者的 5 年移植物存活率为 71.7%，年龄在 1 至 5 岁的为 74.9%，年龄在 6 至 10 岁的为 78.9%，年龄在 11 至 17 岁的为 77.4%。