豌豆蛋白口服补充剂在抗阻训练期间可促进肌肉厚度增加：一项双盲、随机、安慰剂对照的临床试验与乳清蛋白对比。
Pea proteins oral supplementation promotes muscle thickness gains during resistance training: a double-blind, randomized, Placebo-controlled clinical trial vs. Whey protein.
作者信息
Babault Nicolas, Païzis Christos, Deley Gaëlle, Guérin-Deremaux Laetitia, Saniez Marie-Hélène, Lefranc-Millot Catherine, Allaert François A
机构信息
National Institute for Health and Medical Research, (INSERM), unit 1093, Cognition, Action and Sensorimotor Plasticity, Dijon, France ; Centre for Performance Expertise, UFR STAPS, Dijon, France ; Faculté des Sciences du Sport, Université de Bourgogne, BP 27877, 21078 Dijon Cedex, France.
National Institute for Health and Medical Research, (INSERM), unit 1093, Cognition, Action and Sensorimotor Plasticity, Dijon, France ; Centre for Performance Expertise, UFR STAPS, Dijon, France.
出版信息
J Int Soc Sports Nutr. 2015 Jan 21;12(1):3. doi: 10.1186/s12970-014-0064-5. eCollection 2015.
BACKGROUND
The effects of protein supplementation on muscle thickness and strength seem largely dependent on its composition. The current study aimed at comparing the impact of an oral supplementation with vegetable Pea protein (NUTRALYS®) vs. Whey protein and Placebo on biceps brachii muscle thickness and strength after a 12-week resistance training program.
METHODS
One hundred and sixty one males, aged 18 to 35 years were enrolled in the study and underwent 12 weeks of resistance training on upper limb muscles. According to randomization, they were included in the Pea protein (n = 53), Whey protein (n = 54) or Placebo (n = 54) group. All had to take 25 g of the proteins or placebo twice a day during the 12-week training period. Tests were performed on biceps muscles at inclusion (D0), mid (D42) and post training (D84). Muscle thickness was evaluated using ultrasonography, and strength was measured on an isokinetic dynamometer.
RESULTS
Results showed a significant time effect for biceps brachii muscle thickness (P < 0.0001). Thickness increased from 24.9 ± 3.8 mm to 26.9 ± 4.1 mm and 27.3 ± 4.4 mm at D0, D42 and D84, respectively, with only a trend toward significant differences between groups (P = 0.09). Performing a sensitivity study on the weakest participants (with regards to strength at inclusion), thickness increases were significantly different between groups (+20.2 ± 12.3%, +15.6 ± 13.5% and +8.6 ± 7.3% for Pea, Whey and Placebo, respectively; P < 0.05). Increases in thickness were significantly greater in the Pea group as compared to Placebo whereas there was no difference between Whey and the two other conditions. Muscle strength also increased with time with no statistical difference between groups.
CONCLUSIONS
In addition to an appropriate training, the supplementation with pea protein promoted a greater increase of muscle thickness as compared to Placebo and especially for people starting or returning to a muscular strengthening. Since no difference was obtained between the two protein groups, vegetable pea proteins could be used as an alternative to Whey-based dietary products.
TRIAL REGISTRATION
The present trial has been registered at ClinicalTrials.gov (NCT02128516).
背景
蛋白质补充剂对肌肉厚度和力量的影响似乎很大程度上取决于其成分。本研究旨在比较口服补充植物豌豆蛋白（NUTRALYS®）与乳清蛋白及安慰剂，在进行12周抗阻训练计划后，对肱二头肌肌肉厚度和力量的影响。
方法
161名年龄在18至35岁的男性参与了本研究，并对上肢肌肉进行了12周的抗阻训练。根据随机分组，他们被纳入豌豆蛋白组（n = 53）、乳清蛋白组（n = 54）或安慰剂组（n = 54）。在为期12周的训练期间，所有人每天都要服用25克蛋白质或安慰剂两次。在入组时（D0）、训练中期（D42）和训练后（D84）对肱二头肌进行测试。使用超声评估肌肉厚度，并在等速测力计上测量力量。
结果
结果显示肱二头肌肌肉厚度有显著的时间效应（P < 0.0001）。在D0、D42和D84时，厚度分别从24.9±3.8毫米增加到26.9±4.1毫米和27.3±4.4毫米，各组之间仅有显著差异的趋势（P = 0.09）。对最弱的参与者（就入组时的力量而言）进行敏感性研究，各组之间厚度增加有显著差异（豌豆组、乳清蛋白组和安慰剂组分别为+20.2±12.3%、+15.6±13.5%和+8.6±7.3%；P < 0.05）。与安慰剂组相比，豌豆组的厚度增加显著更大，而乳清蛋白组与其他两组之间没有差异。肌肉力量也随时间增加，各组之间无统计学差异。
结论
除了适当的训练外，与安慰剂相比，补充豌豆蛋白能使肌肉厚度有更大增加，尤其是对于刚开始或重新开始进行肌肉强化训练的人。由于两组蛋白质组之间没有差异，植物豌豆蛋白可作为基于乳清蛋白的膳食产品的替代品。
试验注册
本试验已在ClinicalTrials.gov（NCT02128516）注册。
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