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儿童精神分裂症样人格墨尔本评估:儿童分裂样人格障碍的一种有效测量方法。

The Melbourne assessment of Schizotypy in kids: a useful measure of childhood schizotypal personality disorder.

作者信息

Jones Harvey P, Testa Renee R, Ross Nola, Seal Marc L, Pantelis Christos, Tonge Bruce

机构信息

School of Psychology and Psychiatry, Monash University, Clayton, VIC 3800, Australia ; Department of Psychiatry, Melbourne Neuropsychiatry Centre, University of Melbourne, Carlton South, VIC 3053, Australia.

School of Psychology and Psychiatry, Monash University, Clayton, VIC 3800, Australia ; Department of Psychiatry, Melbourne Neuropsychiatry Centre, University of Melbourne, Carlton South, VIC 3053, Australia ; Child and Adolescent Neuropsychology Group, East Melbourne, VIC 3002, Australia.

出版信息

Biomed Res Int. 2015;2015:635732. doi: 10.1155/2015/635732. Epub 2015 Jan 6.

Abstract

Despite being identified as a high risk cohort for psychosis, there has been relatively little research on the clinical presentation and assessment of Schizotypal Personality Disorder (SPD) in childhood. The current study aimed to develop a measure of childhood SPD (Melbourne Assessment of Schizotypy in Kids (MASK)) and assess discriminant validity against another neurodevelopmental disorder, autism spectrum disorder (ASD). Sixty-eight children aged between 5 and 12 (21 SPD, 15 ASD, and 32 typically developing) and their parents were administered the MASK. The MASK is a 57-item semistructured interview that obtains information from the child, their parents, and the clinician. The results showed high internal consistency for the MASK and higher scores in the SPD group. A factor analysis revealed two MASK factors: social/pragmatic symptoms and positive schizotypal symptoms. Both factors were associated with SPD, while only the social/pragmatic factor was associated with ASD. Within the two clinical groups, a receiver operating characteristic curve showed that the MASK (cut-off score: 132 out of 228) was a good indicator of SPD diagnosis. These preliminary MASK findings were reliable and consistent and suggest that childhood SPD is characterised by complex symptomology distinguishable from ASD.

摘要

尽管分裂型人格障碍(SPD)被认定为精神病的高危群体,但针对儿童期SPD临床表现及评估的研究相对较少。本研究旨在开发一种儿童期SPD的测量工具(墨尔本儿童分裂型人格障碍评估量表(MASK)),并评估其相对于另一种神经发育障碍——自闭症谱系障碍(ASD)的判别效度。对68名年龄在5至12岁之间的儿童(21名患有SPD、15名患有ASD以及32名发育正常)及其父母进行了MASK测试。MASK是一个包含57个条目的半结构化访谈,从儿童、其父母以及临床医生处获取信息。结果显示,MASK具有较高的内部一致性,且SPD组得分更高。一项因子分析揭示了MASK的两个因子:社交/实用症状和阳性分裂型人格障碍症状。这两个因子均与SPD相关,而只有社交/实用因子与ASD相关。在两个临床组中,一条受试者工作特征曲线显示,MASK(临界分数:228分中的132分)是SPD诊断的良好指标。MASK的这些初步研究结果可靠且一致,表明儿童期SPD具有可与ASD区分的复杂症状特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12be/4300034/dc0a5e56ad7e/BMRI2015-635732.001.jpg

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