Ling Min-Pei, Lien Keng-Wen, Wu Chiu-Hua, Ni Shih-Pei, Huang Hui-Ying, Hsieh Dennis P H
Department of Health Risk Management, China Medical University , No. 91 Hsueh-Shih Road, Taichung, 40402 Taiwan R.O.C.
J Agric Food Chem. 2015 Feb 25;63(7):2074-82. doi: 10.1021/jf503987y. Epub 2015 Feb 12.
The purpose was to assess the health risk to general consumers in Taiwan associated with dietary intake of benzoic acid and sorbic acid by conducting a total diet study (TDS). The hazard index (HI) in percent acceptable daily intake (%ADI) of benzoic acid and sorbic acid for eight exposure groups classified by age were calculated. In high-intake consumers, the highest HI of benzoic acid was 54.1%ADI for males aged 1-2 years old at the 95th percentile, whereas for females, the HI was 61.7%ADI for aged over 66 years old. The highest HI of sorbic acid for male and female consumers aged 3-6 years old at the 95th percentile were 14.0%ADI and 12.2%ADI, respectively. These results indicate that the use of benzoic acid and sorbic acid as preservatives at the current level of use in the Taiwanese diet does not constitute a public health and safety concern.
目的是通过开展总膳食研究(TDS)来评估台湾地区一般消费者因膳食摄入苯甲酸和山梨酸而面临的健康风险。计算了按年龄分类的八个暴露组中苯甲酸和山梨酸相对于每日允许摄入量百分比(%ADI)的危害指数(HI)。在高摄入量消费者中,苯甲酸的最高HI在第95百分位数时,1至2岁男性为54.1%ADI,而对于女性,66岁以上者的HI为61.7%ADI。第95百分位数时,3至6岁男性和女性消费者中山梨酸的最高HI分别为14.0%ADI和12.2%ADI。这些结果表明,在台湾饮食目前的使用水平下,将苯甲酸和山梨酸用作防腐剂不会构成公共卫生和安全问题。