Klernäs Pia, Johnsson Aina, Horstmann Vibeke, Kristjanson Linda J, Johansson Karin
Division of Physiotherapy, Department of Health Science, Lund University, Lund, Sweden,
Qual Life Res. 2015 Feb;24(2):427-39. doi: 10.1007/s11136-014-0783-8. Epub 2015 Jan 30.
The purpose of this study was to reduce the 188-item Swedish Lymphedema Quality of Life Inventory (SLQOLI) to an abbreviated, clinically useful version (phase 1) and to test it for reliability and validity (phase 2).
In phase 1 correlation analysis, factor analysis, content validity assessment and expert panels were used to reduce the number of items in SLQOLI to 45 items, which was named, Lymphedema Quality of Life Inventory (LyQLI). In phase 2, LyQLI was sent to 200 patients with lymphedema. 126 patients completed the questionnaire twice to determine stability of the instrument over time. SF-36 was sent to the patients once, correlations between the three domains in LyQLI and the two sum scores Physical Health (PCS) and Mental Health (MCS) in SF-36 were used to assess concurrent validity.
The 188-item SLQOLI was reduced to 45-item LyQLI. Four domains were reduced to three: physical, psychosocial and practical. Reliability estimates using ICC for the physical and psychosocial domains were 0.88 (p < 0.01) and 0.87 (p < 0.01), for the practical domain 0.87 (p < 0.01). Cronbach's alpha coefficients for the three domains were 0.88, 0.92 and 0.88, respectively. The physical domain correlated highly significantly with PCS, psychosocial highly significantly with MCS and practical equally highly significantly to both PCS and MCS. Using skewness coefficients, small floor effects in the items were found.
The shorter LyQLI demonstrated good reliability and validity with potential use to assess quality of life in clinic settings and in further cross-sectional studies of patients with lymphedema.
本研究的目的是将188项的瑞典淋巴水肿生活质量量表（SLQOLI）简化为一个简短的、具有临床实用性的版本（第一阶段），并对其进行信度和效度测试（第二阶段）。
在第一阶段，采用相关分析、因子分析、内容效度评估和专家小组，将SLQOLI的项目数减少至45项，命名为淋巴水肿生活质量量表（LyQLI）。在第二阶段，将LyQLI发送给200名淋巴水肿患者。126名患者两次完成问卷，以确定该工具随时间的稳定性。向患者发送一次SF-36，利用LyQLI的三个领域与SF-36中的身体健康（PCS）和心理健康（MCS）两个总分之间的相关性来评估同时效度。
188项的SLQOLI被简化为45项的LyQLI。四个领域减少为三个：身体、心理社会和实际。使用组内相关系数（ICC）对身体和心理社会领域的信度估计分别为0.88（p<0.01）和0.87（p<0.01），实际领域为0.87（p<0.01）。三个领域的克朗巴哈α系数分别为0.88、0.92和0.88。身体领域与PCS高度显著相关，心理社会领域与MCS高度显著相关，实际领域与PCS和MCS均高度显著相关。利用偏度系数，发现项目中存在较小的地板效应。
较短的LyQLI表现出良好的信度和效度，有潜力用于临床环境中评估生活质量以及进一步对淋巴水肿患者进行横断面研究。
