Lu Lei, Liu Min, Sun RongRong, Zheng Yi, Zhang Peiying
Graduate School, Nanjing University of Chinese Medicine, Nanjing, 210023, Jiangsu, China.
Department of Cardiology, Xuzhou Central Hospital, 199# South Jiefang Road, Xuzhou, 221009, Jiangsu, China.
Cell Biochem Biophys. 2015 Jul;72(3):865-7. doi: 10.1007/s12013-015-0553-4.
Myocardial infarction (MI) is a term used for an event of heart attack which is due to formation of plaques in the interior walls of the arteries resulting in reduced blood flow to the heart and injuring heart muscles because of lack of oxygen supply. The symptoms of MI include chest pain, which travels from left arm to neck, shortness of breath, sweating, nausea, vomiting, abnormal heart beating, anxiety, fatigue, weakness, stress, depression, and other factors. The immediate treatment of MI include, taking aspirin, which prevents blood from clotting, and nitro-glycerin to treat chest pain and oxygen. The heart attack can be prevented by taking an earlier action to lower those risks by controlling diet, fat, cholesterol, salt, smoking, nicotine, alcohol, drugs, monitoring of blood pressure every week, doing exercise every day, and loosing body weight. The treatment of MI includes, aspirin tablets, and to dissolve arterial blockage injection of thrombolytic or clot dissolving drugs such as tissue plasminogen activator, streptokinase or urokinase in blood within 3 h of the onset of a heart attack. The painkillers such as morphine or meperidine can be administered to relieve pain. Nitroglycerin and antihypertensive drugs such as beta-blockers, ACE inhibitors or calcium channel blockers may also be used to lower blood pressure and to improve the oxygen demand of heart. The ECG, coronary angiography and X-ray of heart and blood vessels can be performed to observe the narrowing of coronary arteries. In this article the causes, symptoms and treatments of MI are described.
心肌梗死(MI)是用于描述心脏病发作事件的术语,它是由于动脉内壁形成斑块,导致心脏血流减少,因缺氧而损伤心肌。心肌梗死的症状包括胸痛(疼痛从左臂放射至颈部)、呼吸急促、出汗、恶心、呕吐、心跳异常、焦虑、疲劳、虚弱、压力、抑郁以及其他症状。心肌梗死的紧急治疗包括服用阿司匹林(防止血液凝固)、硝酸甘油治疗胸痛以及吸氧。通过采取早期行动,如控制饮食、脂肪、胆固醇、盐的摄入,戒烟、避免尼古丁和酒精、药物,每周监测血压,每天进行锻炼以及减轻体重等措施来降低风险,可以预防心脏病发作。心肌梗死的治疗包括服用阿司匹林片,以及在心脏病发作后3小时内通过注射溶栓药物(如组织纤溶酶原激活剂、链激酶或尿激酶)来溶解动脉堵塞。可使用吗啡或哌替啶等止痛药来缓解疼痛。硝酸甘油和降压药物,如β受体阻滞剂、血管紧张素转换酶抑制剂或钙通道阻滞剂,也可用于降低血压并改善心脏的氧气需求。可以进行心电图、冠状动脉造影以及心脏和血管的X射线检查,以观察冠状动脉的狭窄情况。本文描述了心肌梗死的病因、症状和治疗方法。